background: prostate cancer after lung cancer is the second cause of cancer-associated death in men. in recent years, targeted therapy of cancer has attracted researchers attention. the targeted therapy lead to decrease in side effects of drugs. studies have indicated that targeting peptides for cancer cells represent valuable tools for diagnostic and therapeutic. recently, phage display peptid...

background & importance: infections of the craniocervical junction are rare. case presentation: we present a case of infection by methicillin-sensitive staphylococcus aureus and streptococcus mitis that was not previously reported. conclusion: neurosurgeons must suspect for diagnosis and initiate broad antimicrobial therapy, including active agents against gram-negative and then initiate a targ...

Glioblastoma (GBM) represents the most frequent primary brain tumor in adults and carries a dismal prognosis despite aggressive, multimodal treatment regimens involving maximal resection, radiochemotherapy, and maintenance chemotherapy. Histologically, GBMs are characterized by a high degree of VEGF-mediated vascular proliferation. In consequence, new targeted anti-angiogenic therapies, such as...

Background & Importance: Infections of the craniocervical junction are rare. Case Presentation: We present a case of infection by methicillin-sensitive Staphylococcus aureus and Streptococcus mitis that was not previously reported. Conclusion: Neurosurgeons must suspect for diagnosis and initiate broad antimicrobial therapy, including active agents against gram-negative and then...

The oral cavity is colonized by a large number and highly diversified communities of micro-organisms. Bacterial biofilm present on tooth or root surface is a major cause of gingivitis and periodontitis. Chemical antimicrobial agents are widely used in prophylactic and therapeutic regimens for dental plaque related diseases, which are among the most common human infections. As these agents are d...

transcatheter ablation of atrioventricular accessory pathway is the therapy of choice in symptomatic patients. the ablation of posteroseptal accessory pathways thas some important points due to its anatomical location. catheter ablation of posteroseptal accessory pathways via left side approach is time consuming with low success rate and higher complications. we performed successful transcathet...

Numerous studies have indicated that in cancer treatment Chinese herbal medicines in combination with chemo- or radio-therapy can be used to enhance the efficacy of and diminish the side effects and complications caused by chemo- and radio-therapy. Therefore, an understanding of Chinese herbal medicines is needed by physicians and other health care providers. This review provides evidence for u...

Proper use of climatic forecast information in planning and implementing agricultural activities is critical for the improvement of the wellbeing of smallholder farmers whose livelihoods depend on rain-fed agriculture. This study employed a descriptive cross-sectional design involving 12 focus group discussions and 255 household interviews to determine the extent to which smallholder farmers in...