In the title compound, C(9)H(5)N(3), the quinoxaline ring is essentially planar, with a maximum deviation of 0.012 (1) Å. Short inter-molecular distances between the centroids of the 2,3-dihydro-pyrazine and benzene rings [3.6490 (5) Å] indicate the existence of π⋯π inter-actions. In the crystal packing, the mol-ecules are linked via two pairs of inter-molecular C-H⋯N inter-actions, forming R(2...

The asymmetric unit of the title compound, C(11)H(12)N(2)O, contains two independent mol-ecules. In the crystal structure, inter-molecular C-H⋯O hydrogen bonds link the mol-ecules. There are π-π contacts between the quinoxaline rings [centroid-centroid distances = 3.446 (2), 3.665 (2), 3.645 (3) and 3.815 (3) Å]. There also exist C-H⋯π contacts between the methyl groups and the quinoxaline rings.

Abstract Aromatic carboxylic acids are prone to decarboxylate in high-temperature water (HTW). While the decarboxylation kinetics of several aromatic have been explored, studies on their compatibility with organic syntheses HTW scarce. Herein, we report hydrothermal synthesis (HTS) 2,3-diarylquinoxaline from 1,2-diarylketones and 3,4-diaminobenzoic acid. A detailed study reaction parameters was...

In the title spiro-indeno-quinoxaline compound, C(22)H(14)N(6)O·C(2)H(6)O, the five-membered ring of the indene unit and the pyran ring are perpendicular [89.11 (3)°]. In the crystal, N-H⋯N hydrogen bonds connect the spiro-indeno-quinoxaline mol-ecules, and the ethanol solvent mol-ecules complete the hydrogen-bond network via O-H⋯N and N-H⋯O inter-actions.

The excellent catalytic activity of newly magnetic nanocatalyst FeAl 2 O 4 @PTMS-sulfaguanidine-SA in a one pot multicomponent Mannich-type reaction was used to obtain 2-piperazinyl quinoxaline derivatives with highly selective anti-proliferation efficacy.

Echinomycin, a member of the quinoxaline family of antibiotics, is known to be a strong inhibitor of RNA synthesis which has been attributed to its ability to bind to double-helical DNA. Here we study the effect of echinomycin upon DNA replication using egg extracts and embryos from Xenopus laevis as well as cultured human cells. Evidence is presented that echinomycin interferes with chromatin ...

Quinoxaline, organotin, organofluorine, and formamidine compounds are among the newer pesticide chemicals used for acarine control. Included in these four classes are some of the most selective synthetic organic toxicants currently in the acaricide/insecticide arsenal. Oxythioquinox, Plictran (tricyclohexylhydroxytin), Nissol [2-fluoro-N-methyl-N-(1-naphthyl)acetamide], and chlordimeform are ex...