OBJECTIVE We investigate how known differences in myelin architecture between regions along the cortico-spinal tract and frontal white matter (WM) in 19 healthy adolescents are reflected in several quantitative MRI parameters that have been proposed to non-invasively probe WM microstructure. In a clinically feasible scan time, both conventional imaging sequences as well as microstructural MRI p...

The spin transfer phenomenon provides a new method to manipulate magnetization without applying an external magnetic field and a new playground to study the spin degree of freedom of electrons. Two types of magnetic dynamics excited by the spin transfer torque from a direct current were predicted in 1996: magnetization reversal and steady-state precession. The physics of spin-torque-induced mag...

Objectives To assess whether quantitative spinal cord MRI (SC-MRI) measures, including atrophy, and diffusion tensor imaging (DTI) and magnetization transfer imaging metrics were different in radiologically isolated syndrome (RIS) vs healthy controls (HCs). Methods Twenty-four participants with RIS and 14 HCs underwent cervical SC-MRI on a 3T magnet. Manually segmented regions of interest cir...

Introduction Recent studies [1] revealed that balanced SSFP shows a pronounced magnetization transfer (MT) contrast, which can be altered via the RF pulse duration and thus allows for quantitative MT imaging [2]. It is thereby assumed that changes in signal intensity are due to the MT effect alone. However, elongated RF pulses entail a prolonged TR, which may introduce signal variations due to ...