BACKGROUND Greater quadriceps strength has been associated with lower risk of symptomatic knee osteoarthritis (OA) in older adults. However, factors that confer elevated risk of knee OA (eg, sedentary lifestyle, obesity, and knee injury) also contribute to a reduced tolerance of resistance training programs at ≥60% 1-repetition maximum (1RM). Therefore, the current study assessed whether concur...

OBJECTIVES To investigate the effect of pyridostigmine on fatigue, physical performance, and muscle function in subjects with postpoliomyelitis syndrome. METHODS 67 subjects with increased fatigue and new weakness in one quadriceps muscle showing neuromuscular transmission defects, were included in a randomised, double blind, placebo controlled trial of 60 mg pyridostigmine four times a day f...

BACKGROUND AND PURPOSE Despite evidence of weakness in children with cerebral palsy, the use of strength training in this population remains controversial. SUBJECTS Fourteen children with spastic diplegia, ranging in age from 6 to 14 years (X = 9.1, SD = 2.5), participated in a bilateral quadriceps femoris muscle strengthening program. METHODS The children exercised three times per week for...

Background: Although quadriceps weakness is well recognised in chronic obstructive pulmonary disease (COPD), the aetiology remains unknown. In disabled patients the quadriceps is a particularly underused muscle and may not reflect skeletal muscle function as a whole. Loss of muscle function is likely to be equally distributed if the underlying pathology is a systemic abnormality. Conversely, if...

The aim of the present study was to investigate the prevalence of muscle weakness and the importance of physical inactivity in cystic fibrosis (CF), and its relationship to exercise tolerance and muscle strength. Exercise tolerance, skeletal and respiratory muscle strength were studied in a group of 64 adults with CF (age 26+/-8 yrs, FEV(1 % predicted) 65+/-19) and in 20 age-matched controls. P...

In recent years, adductor canal block (ACB) has been introduced as an alternative for femoral nerve block with a great advantage of preserving or minimally reducing quadriceps strength. The technique is relatively easy and is performed under ultrasound guidance. Despite growing evidence regarding efficacy and safety of ACB following knee surgery, use of ACB is still limited to high volume ortho...

Simultaneous bilateral TKA (SBTKA) has been a favored surgical solution due to reduced costs and patient suffering. The purpose of the present study was to investigate the risk factors of asymmetric recovery in patients who underwent SBTKA and whether that affected quality of life. A total of 187 patients undergoing SBTKA were included. During this study, patients underwent physical examination...

BACKGROUND Knee reinjury after ACL reconstruction is common and increases the risk of osteoarthritis. There is sparse evidence to guide return to sport (RTS) decisions in this population. OBJECTIVES To assess the relationship between knee reinjury after ACL reconstruction and (1) return to level I sports, (2) timing of RTS and (3) knee function prior to return. METHODS 106 patients who part...

In 2000, body composition, x-ray-defined knee osteoarthritis, and self-reported knee pain information from a cross-sectional, community-based study of 211 African-American and 669 Caucasian women in southeast Michigan (mean age, 47 years) was related to performance-based physical functioning measures to characterize development of functional limitations. Body composition was assessed with bioel...

OBJECTIVE We aimed to compare the efficacies of rehabilitation with the hybrid assistive limb and conventional rehabilitation after total knee arthroplasty. MATERIALS AND METHODS A total of 37 consecutive patients who underwent primary total knee arthroplasty for knee osteoarthritis were enrolled. Seven patients withdrew from the study after randomization, and 30 patients (hybrid assistive li...