1. Abstract 2. Introduction 3. Purine and pyrimidine metabolism during somatic embryogenesis 3.1. Maintenance of embryogenic tissue 3.1.1. Purine metabolism during maintenance of embryogenic tissue 3.1.2. Pyrimidine metabolism during maintenance of embryogenic tissue 3.2. Development of somatic embryos 3.2.1. Purine metabolism during development of somatic embryos 3.2.2. Pyrimidine metabolism d...

We demonstrate here that 8-amino guanine () strongly accelerates quadruplex formation, which makes this nucleobase the most attractive replacement for guanine in the context of tetramolecular parallel quadruplexes.

Aim: To study the effect of new synthesized pyrimidine derivatives on growth Mycobacterium lufu ( M. ) and tuberculosis when cultivated Shkolnikova’s medium. Materials methods. The objects research were 6 samples - 5-(arylmethylidene)-2,4,6-pyrimidine-2,4,6(1 H ,3 ,5 )-trions under laboratory codes TAG1, TAG2, TAG3, TAG4, TAG5, TAG6 7 5-(getarylmethylidene)-2,4,6-pyrimidine-2,4,6(1 , 3 5 TAG7, ...

acylisothiocyanate (1) was allowed to react with benzylidene malononitrile producing oxazine derivative (2). also, compound (1) was reacted with sodium azide followed by refluxing with sodium ethoxide affording thiazinotetrazole derivative (4). the reaction of acetylacetone with compound (1) gave pyridine derivative (5) by intramolecular cycloaddition while it was reacted with n-methyl aniline ...

Amphiphilic nucleobase-containing block copolymers with poly(oligo(ethylene glycol) methyl ether methacrylate) as the hydrophilic block and nucleobase-containing blocks as the hydrophobic segments were successfully synthesized using RAFT polymerization and then self-assembled via solvent switch in aqueous solutions. Effects of the common solvent on the resultant morphologies of the adenine (A) ...

Purine nucleoside and nucleobase transporters are of fundamental importance for Trypanosoma brucei and related kinetoplastid parasites because these protozoa are not able to synthesize purines de novo and must salvage the compounds from their hosts. In the studies reported here, we have identified a family of six clustered genes in T. brucei that encode nucleoside/nucleobase transporters. These...