نتایج جستجو برای: pyridoxine

تعداد نتایج: 1897  

Journal: :Fetal diagnosis and therapy 2008
Paddy Jim Baggot Anna Jane Y Eliseo Nathaniel G DeNicola Jeremy A Kalamarides James D Shoemaker

INTRODUCTION Some studies of children with Down syndrome have found mild abnormalities in the metabolism of pyridoxine (vitamin B(6)); therefore the present question is whether such abnormalities might also be present in the amniotic fluid of fetuses with Down syndrome. MATERIALS AND METHODS Archived specimens of amniotic fluid were obtained from chromosomally normal and from fetuses with Dow...

Journal: :The British journal of nutrition 1994
P G Massé K P Pritzker M G Mendes A L Boskey H Weiser

In the present study the effect of pyridoxine deficiency on the ultrastructure and morphology of bone and its metabolism was examined in the rapidly growing chick. Pyridoxine-deficient animals had tibias of reduced dry weight and cortical thickness. Histomorphometry demonstrated a disproportionately high eroded surface, lower amount of osteoid tissue and reduced mineralized trabecular width. An...

Journal: :Journal of nutritional science and vitaminology 2002
Shun-Ichiro Komatsu Hiromitsu Watanabe Tatsuzo Oka Haruhito Tsuge Norihisa Kat

Recently we reported that the supplementation of vitamin B6 to low vitamin B6 diet caused suppression in colon tumorigenesis and cell proliferation of azoxymethane-treated mice in a dose-dependent manner among 1, 7, and 14 mg pyridoxine HCl/kg diet (J. Nutr. 131: 2204-2207, 2001). To examine the mechanism of the anticolon tumor effect of vitamin B6, male ICR mice were fed the diet containing 1,...

Journal: :iranian journal of pharmaceutical research 0
parvin parsaei department of chemistry, islamic azad university, north tehran branch, tehran, iran manouchehr bahmaei department of chemistry, islamic azad university, north tehran branch, tehran, iran. alireza ghannadi school of pharmacy and pharmaceutical sciences and isfahan pharmaceutical research center, isfahan university of medical sciences, isfahan, iran.

dispersive liquid-liquid microextraction method (dllme) combined with high-performance liquid chromatography-ultraviolet detection (hplc-uv) was used to determine thiamine (b1), nicotinamide (b3) and pyridoxine (b6) in sour cherry juice. this method was rapid, simple and sensitive. separation was accomplished using a c18 column. the optimum chromatographic conditions were found to be: mobile ph...

2008
Jin-Young Chung Jung-Hoon Choi Cheol-Yong Hwang Hwa-Young Youn

To construct a sensory neuropathy model, excess pyridoxine (150 mg/kg s.i.d.) was injected subcutaneously in dogs over a period of 7 days. During the administrations period, the dogs experienced body weight reduction and proprioceptive loss involving the hindquarters. After pyridoxine administration was completed, electrophysiological recordings showed that the M wave remained at a normal state...

Journal: :Applied and environmental microbiology 2003
Koichi Wada Yasuhisa Asano

Nearly 100% 5'-position selectivity of transglucosylation from maltodextrin to pyridoxine (PN) by cells of Verticillium dahliae TPU 4900 was observed when the reaction was carried out with borate. The same effect of borate was observed not only during synthesis of pyridoxine 5'-alpha-D-glucoside by partially purified enzyme of this strain but also during synthesis of this compound by other micr...

Journal: :Bioscience, biotechnology, and biochemistry 2008
Yoshie Nagahashi Masaaki Tazoe Tatsuo Hoshino

A novel gene (pdxP) encoding a pyridoxine 5'-phosphate (PNP) phosphatase involved in the last step of pyridoxine biosynthesis was cloned from Sinorhizobium meliloti IFO 14782 on the basis of the peptide sequences of the natural enzyme. The pdxP gene is an open reading frame (708 bp) encoding 235 amino acid residues with a calculated molecular weight of 26,466. From its deduced amino acid sequen...

Journal: :Journal of Medical Case Reports 2008
Francois Maillot Jan P Kraus Philip J Lee

INTRODUCTION Non-heritable factors may have an influence on the clinical expression of monogenic inherited metabolic diseases. CASE PRESENTATION This is a case report of a man whose mother had been diagnosed late in childhood with pyridoxine responsive homocystinuria with lens dislocation and neurodevelopmental delay. These severe complications were not observed in her son who was pyridoxine ...

Journal: :British medical journal 1975
H J Bennink W H Schreurs

Fourteen pregnant women were shown by the oral glucose tolerance test to have gestational diabetes. In 13 an increased urinary xanthurenic-acid excretion after an oral load of L-tryptophan indicated a relative pyridoxine deficiency. All patients were treated with vitamin B6 (pyridoxine) 100 mg/day for 14 days by mouth, after which the pyridoxine deficiency disappeared and the oral glucose toler...

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