In the presence of water lithium tetrahydroborate is capable of reducing pyridine to 1,4dihydropyridine. The product, lithiumtetrakis(pyridine) tetrakis(1,4-hydropyridyl)borate, was isolated and characterized by NMR and IR spectroscopy and single crystal X-ray diffraction. [Li(py)4][B(pyH)4]2(1,4-dioxane) crystallized in space group P42/n, Z = 2. Similarly, NaBH4 can also reduce pyridine in the...

Mitochondria from normal rat liver and heart, and also Ehrlich tumor cells, respiring on succinate as energy source in the presence of rotenone (to prevent net electron flow to oxygen from the endogenous pyridine nucleotides), rapidly take up Ca(2+) and retain it so long as the pyridine nucleotides are kept in the reduced state. When acetoacetate is added to bring the pyridine nucleotides into ...

The crystal structure of the title compound, [Cu(2)Cl(4)(C(10)H(8)N(2)O(2)S)(2)(H(2)O)(2)], comprises neutral centrosymmetric μ-chloride-bridged dinuclear units. Each Cu(II) ion is penta-coordinated by three chloride ligands, a pyridine N-oxide O atom and a water mol-ecule. Intra- and inter-molecular O-H⋯O hydrogen bonds occur between the coordinated water mol-ecules and the uncoordinated and c...

Five new NNN pincer-type ligands and their palladium complexes were successfully synthesised characterised by FT-IR, 1H NMR, 13C UV–vis analyses. TEM analysis was used to observe the morphological character of black residues obtained from fourth cycle reusability test. Furthermore, suitable crystals N2,N6-bis(2-tert-butylphenyl)pyridine-2,6-dicarboxamide its complex elucidated with X-ray single...

In an earlier communication (I), Griffith and Byerrum reported that succinate-2,3-r4C was incorporated into positions 2 and 3 of the pyridine ring of nicotine, and 14C! was distributed essentially equally between the 2 carbon atoms. In addition, ‘4C-labeled glycerol was shown to be efficiently incorporated into the pyridine moiety, and it was suggested that positions 4, 5, and 6 of the ring are...

The Front Cover shows 5-bromo-2-(tetrahydro-2H-pyran-4-yl)pyridine – one of many sp3-enriched pyridine derivatives prepared on a multigram scale by group Ukrainian chemists. background photo Anatolii Varenyk depicts the Kilometre Zero Ukraine Sign (also known as “The Winged Globe”) control point located Independence Square (Maidan Nezalezhnosti) in Kyїv. More information can be found Research A...

Reaction of 2,6-difluoropyridine with 2 equiv of indazole and NaH at room temperature affords a mixture of 2,6-bis(indazol-1-yl)pyridine (1-bip), 2-(indazol-1-yl)-6-(indazol-2-yl)pyridine (1,2-bip), and 2,6-bis(indazol-2-yl)pyridine (2-bip), which can be separated by solvent extraction. A two-step procedure using the same conditions also affords both 2-(indazol-1-yl)-6-(pyrazol-1-yl)pyridine (1...

The title compound, C(19)H(19)N(3)O(4)S(2), was prepared by the reaction of 2,3-diamino-pyridine with tosyl chloride in a mixture of dichloro-methane-pyridine as solvent. In the crystal, mol-ecules associate via pairs of N-H⋯N hydrogen bonds, forming a centrosymmetric eight-membered {⋯HNCN}(2) synthon. The dihedral angles between the amino-pyridine ring and the tosyl benzene rings are 50.01 (6)...

The title compound, C(19)H(9)N(5)O(4), has crystallographically imposed twofold rotational symmetry. The asymmetric unit contains one half-mol-ecule. The crystal structure is stabilized by π-π stacking of inversion-related pyrrolo-[3,4-b]pyridine rings, with a centroid-centroid distance between stacked pyridines of 3.6960 (8) Å. The dihedral angle between the central pyridine ring and the pyrro...

The complete mol-ecule of the title compound, [Cd(C(6)H(12)NOS(2))(2)(C(12)H(10)N(4))(2)], is generated by crystallographic inversion symmetry. The distorted octa-hedral trans-N(2)S(4) donor set for the Cd(2+) ion is defined by two symmetrically S,S'-chelating dithio-carbamate anions and two pyridine N atoms derived from two monodentate 4-pyridine-aldazine (or 4-{[(pyridin-4-yl-methyl-idene)hyd...