the potato tuber moth (ptm), phthorimaea operculella zeller (lepidoptera: gelechiidae), is an important pest of potato and other solanaceous plants. it is cosmopolite and oligophage that exists in most countries where potatoes are grown. because of chemical treatment adverse effects, there is a necessity to find safe alternatives to synthetic insecticides. so, medicinal plants are promising sin...

Characterization of the rheological properties of heterogeneous biopolymers is important not only to understand the effect of substrate elasticity on cell behaviors, but also to provide insights into mechanical changes during cellular remodeling of the environment. Conventional particle-tracking microrheology (PTM) techniques are compromised by probe-network slippage and cage-hopping problems, ...

Reactivation of wild-type p53 (wt-p53) function is an attractive therapeutic approach to p53-defective cancers. An ideal p53-based gene therapy should restore wt-p53 production and reduces mutant p53 transcripts simultaneously. In this study, we described an alternative strategy named as trans-splicing that repaired mutant p53 transcripts in hepatocellular carcinoma (HCC) cells. The plasmids wh...

ProteomeScout (https://proteomescout.wustl.edu) is a resource for the study of proteins and their post-translational modifications (PTMs) consisting of a database of PTMs, a repository for experimental data, an analysis suite for PTM experiments, and a tool for visualizing the relationships between complex protein annotations. The PTM database is a compendium of public PTM data, coupled with us...

Reflection Transformation Imaging has proved to be a powerful method to acquire and represent the 3D reflectance properties of an object, displaying them as a 2D image. Recently, Polynomial Texture Maps (PTM), which are relightable images created from a set of photos of the object taken under several different lighting conditions, have been used in Cultural Heritage field to document and virtua...

Platensimycin (PTM) is a recently discovered broad-spectrum antibiotic produced by Streptomyces platensis. It acts by selectively inhibiting the elongation-condensing enzyme FabF of the fatty acid biosynthesis pathway in bacteria. We report here that PTM is also a potent and highly selective inhibitor of mammalian fatty acid synthase. In contrast to two agents, C75 and cerulenin, that are widel...

This study aims to determine the effect of PGF2α injection on post-thaw motility (PTM) in sperm Nubian goats. Three male goats (3-4 years) with good reproductive ability were used. used a 3 x Latin square design. The experimental animals received physiological NaCl as control (P1); 37.5 mg (P2), and 75 (P3). Semen was collected using an artificial vagina one-week storage intervals between treat...

The Persian Traditional Medicine (PTM) system pays special attention to disease prevention. In PTM, physicians believe that overeating may cause accumulation of unhealthy substances in the body and diseases called "Emtela." With respect to ocular health, foods can be categorized as beneficial and harmful. Harmful foods such as beef, geese, eggplant, cauliflower, and cheese can cause reduced vis...

RNA and its associated RNA binding proteins (RBPs) mitigate a diverse array of cellular functions and phenotypes. The interactions between RNA and RBPs are implicated in many roles of biochemical processing by the cell such as localization, protein translation, and RNA stability. Recent discoveries of novel mechanisms that are of significant evolutionary advantage between RBPs and RNA include t...

Potato tuber (Solanum tuberosum) mitochondria (PTM) have a mitochondrially bound hexokinase (HK) activity that exhibits a pronounced sensitivity to ADP inhibition. Here we investigated the role of mitochondrial HK activity in PTM reactive oxygen species generation. Mitochondrial HK has a 10-fold higher affinity for glucose (Glc) than for fructose (KMGlc=140 microM versus KMFrc=1,375 microM). Ac...