نتایج جستجو برای: proviral load
تعداد نتایج: 150243 فیلتر نتایج به سال:
Human T-lymphotropic Virus-1 (HTLV-1) is a retrovirus that persists lifelong by driving clonal proliferation of infected T-cells. HTLV-1 causes a neuroinflammatory disease and adult T-cell leukemia/lymphoma. Strongyloidiasis, a gastrointestinal infection by the helminth Strongyloides stercoralis, and Infective Dermatitis associated with HTLV-1 (IDH), appear to be risk factors for the developmen...
The objective of this paper is to present a general strategy for design optimization of flattop interleavers, and dispersion compensation for the interleavers, in order to achieve superior optical performance. The interleaver is formed by two multi-cavity Gire-Tournois etalons (MC-GTE) in a Michelson Interferometer (MI). An interleaver that has m cavities in one etalon and n cavities in the oth...
Cytokine disregulation has been implicated in the pathogenesis of lentivirus-induced diseases. In the present study, 18 specific pathogen free (SPF) cats were inoculated with feline immunodeficiency virus (FIV) Petaluma strain and sacrificed at different times post-infection. Five additional SPF cats were used as controls. The cell localization of the cytokine tumor necrosis factor alpha (TNF-a...
The Human T lymphotropic virus type-1 (HTLV-1) infects predominantly T cells, inducing proliferation and lymphocyte activation. Additionally, HTLV-1 infected subjects are more susceptible to other infections caused by other intracellular agents. Monocytes/macrophages are important cells in the defense against intracellular pathogens. Our aims were to determine the frequency of monocytes subsets...
The kinetics of HIV-1 decay under treatment depends on the class of antiretrovirals used. Mathematical models are useful to interpret the different profiles, providing quantitative information about the kinetics of virus replication and the cell populations contributing to viral decay. We modeled proviral integration in short- and long-lived infected cells to compare viral kinetics under treatm...
Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of HTLV-associated disease and viral dynamics. A subset of 45 human T-cell lymphotropic virus type 1 (HTLV-1), 45 human T-cell lymphotropic virus ty...
Clonal expansion of infected CD4+ T cells is a major mechanism HIV-1 persistence and barrier to achieving cure. Potential causes are homeostatic proliferation, effects integration, interaction with antigens. Here, we show that it possible link antigen responsiveness, the full proviral sequence, integration site, cell receptor β-chain (TCRβ) sequence examine role recurrent antigenic exposure in ...
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