WHY TEST?  EPM is a neurological disease of the Americas. It is most commonly caused by the parasite Sarcocystis neurona and more rarely by Neospora hughesi.  The standard of practice for diagnosis is to perform a complete neurological exam, accompanied by laboratory tests that detect an immunological response to infection.  Testing of cerebrospinal fluid (CSF), with a paired serum, is more ...

Six plant sources of hydrolyzable tannins (HT) or HT and condensed tannins (CT; designated as HT1, HT2, HT3, HT + CT1, HT + CT2, and HT + CT3) were evaluated to determine their effects in vitro on CH(4) production and on ruminal archaeal and protozoa populations, and to assess potential differences in biological activities between sources containing HT only or HT and CT. Samples HT1, HT2, and H...

Parasitic protozoal infections have long been known to cause profound degrees of sickness and death in humans as well as animal populations. Despite the increase in the number of annotated genomes available for a large variety of protozoa, a great deal more has yet to be learned about them, from their fundamental physiology to mechanisms invoked during host-pathogen interactions. Most of these ...

The purpose of the research is to determine safe parameters for use certain fatty acid amides against protozoal diseases fish. Materials and methods . synthesis biological activity determination new compounds were studied in laboratory conditions chemical creative team North Caucasus Zonal Research Veterinary Institute. protistocidal substances was determined a liquid nutritional medium by seri...

The cyclic GMP-AMP synthase (cGAS)-STING pathway is central for innate immune sensing of various bacterial, viral and protozoal infections. Recent studies identified the common HAQ and R232H alleles of TMEM173/STING, but the functional consequences of these variants for primary infections are unknown. Here we demonstrate that cGAS- and STING-deficient murine macrophages as well as human cells o...

Coccidial parasites of the genus Isospora cause intestinal disease in several mammalian host species. These protozoal parasites have asexual and sexual stages within intestinal cells of their hosts and produce an environmentally resistant cyst stage, the oocyst. Infections are acquired by the ingestion of infective (sporulated) oocysts in contaminated food or water. Some species of mammalian Is...