bioelectronics has attracted increasing interest in recent years because of their applications in various disciplines, such as biomedical. development of efficient bio-nano hybrid materials is a new move towards revolution of nano-bioelectronics. a novel nano-bio hybrid electrode based on zno–protein for bioelectronics applications was prepared and characterized. the electrode was made by coval...

Protein-protein interactions (PPI), in which, two or more proteins associate with each other by various means, are key to understanding all biological processes that occur within as well as between cells. In effect, biological processes are essentially interactions between multiple proteins (Zhang et al., 2011) with PPI networks controlling the flow of information both within and between biolog...

this experiment was conducted to evaluate the effect of different levels of crude protein and threonine on performance, carcass characteristics and immune system of broiler chickens during starter (7-24) and grower (25-42) periods. a total of 288 male broiler chicks of ross 308 strain were used in a completely randomized design with factorial arrangement (2×4) with three replicates in each trea...

The subject of protein-protein interactions represents a vast ensemble of results from biological, biochemical and biophysical studies carried out to date and cannot be treated in its entirety in any reasonable fashion. The following chapter will focus therefore on particular aspects of protein-protein interactions. It will begin with an overview of some classes of protein-protein interactions ...

In the postgenomic era, one of the most interesting and important challenges is to understand protein interactions on a large scale. The physical interactions between protein domains are fundamental to the workings of a cell: in multi-domain polypeptide chains, in multi-subunit proteins and in transient complexes between proteins that also exist independently. Thus experimental investigation of...

In this review, we discuss the structural and functional diversity of protein-protein interactions (PPIs) based primarily on protein families for which three-dimensional structural data are available. PPIs play diverse roles in biology and differ based on the composition, affinity and whether the association is permanent or transient. In vivo, the protomer's localization, concentration and loca...

Human serum albumin (HSA) is the most abundant protein in the blood plasma. Molecular dynamics simulations of subdomain IIA of HSA and its complex with salicylic acid (SAL) were performed to investigate structural changes induced by the ligand binding. To estimate the binding affinity of SAL molecule to subdomains IB and IIA in HSA protein, binding free energies were calculated using the Molecu...

We have studied the changes in protein-protein interaction network of 38 different tissues of the human body. 123 gene expression samples from these tissues were used to construct human protein-protein interaction network. This network is then pruned using the gene expression samples of each tissue to construct different protein-protein interaction networks corresponding to different studied ti...