نتایج جستجو برای: protein candidate

تعداد نتایج: 1323303  

Introduction bacteria species; Burkholderia pseudomallei, Vibrio cholera, and Shigella dysenteriae are the main pathogen causing  Melioidosis, Cholera, and Shigella in humans respectively. bacterial species have a protein that has antigenic prosperities along with being a mucus based adjuvant thus easing their delivery and immunogenicity. These proteins were BLF1(B. pseudomallei), CTxB (V. cho...

Journal: :Clinical complementary medicine and pharmacology 2021

Various vaccine platforms are geared against COVID-19 development to produce immunogens in cells. To design a recombinant protein-based vaccine, Vaxine pty Ltd used computer models of the spike protein and its human receptor, ACE2, identify how virus infects Based on this, COVAX-19? is synthesized. It does reduce not only disease but also blocks shedding transmission. Researchers optimistic tha...

Journal: :iranian journal of biotechnology 2013
asghar tanomand shahin najar peerayeh safar farajnia jafar majidi

background: antibiotic resistance and the need for long-term treatments especially for chronic infections necessitate the developmentof a vaccine against pseudomonas aeruginosa infection.objectives: in this study, recombinant exotoxin a (domains i and ii), (exoa i-ii) protein was expressed, purifid and its immunologicalcharacteristics were evaluated in a mouse model.materials and methods: the g...

Journal: :Parkinsonism & Related Disorders 2021

Mitochondria membrane protein-associated neurodegeneration (MPAN) neurodegenerative disorder is typically associated with biallelic C19orf12 variants. Here we describe a new and review candidate previous monoallelic de novo variants to define loss of function mutations located in the putative non-membrane spanning isoform as potential basis MPAN.

ژورنال: یافته 2018
اسماعیلی, احمد, درویش نیا, مصطفی, نظری, زیبا, نظریان فیروز آبادی, فرهاد,

Background: Root hair culture is a valuable system to produce recombinant proteins in planta. Antimicrobial peptides (AMPs) are  vital parts of the innate immune response found in almost all forms of life. Precise target activity and limited toxicity towards mammalian cells make them suitable candidate molecules to combat evolving drug-resistant microorganisms. The aim of the present study...

Journal: :modares journal of medical sciences: pathobiology 2011
zahra ehsaei jafar salimian shahram nazrian maysam mansouri jafar amani

objective: enterotoxigenic escherichia coli is considered as the most important agent of children diarrhea and mortality in developing countries. this bacterium causes 300-600 thousands of deaths in the children under 5 years of age per year. with difficulties in treatment as well as its wide prevalence, designing an effective vaccine against this microorganism is the objective of world health ...

Journal: :vaccine research 0
maryam golshani departmant of molecular biology, pasteur institute of iran, tehran, iran payam zandi departmant of molecular biology, pasteur institute of iran, tehran, iran saeid bouzari departmant of molecular biology, pasteur institute of iran, tehran, iran

introduction: omp31 is animmunodominant and protective antigen conserved in brucella species and a good candidate for vaccine design. material & methods: the present study aimed at in silico design of the truncated omp31 (tomp31) using bioinformatic tools and to express the selected form in escherichia coli (e. coli) results and conclusion: various bioinformatically calculated scores for the mo...

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