نتایج جستجو برای: prostaglandin e
تعداد نتایج: 1038915 فیلتر نتایج به سال:
Prostaglandins and vasoactive amines in cerebral vasospasm after aneurysmal subarachnoid hemorrhage.
Five consecutively admitted patients with aneurysmal subarachnoid hemorrhage were treated with an indwelling lumbar spinal catheter. Daily samples of cerebrospinal fluid were analyzed for erythrocyte, protein, glucose, dopamine, epinephrine, serotonin, 5-hydroxyindoleacetic acid, tryptophan, histamine, thromboxane, 6-ketoprostaglandin F1 alpha, prostaglandin E, and prostaglandin F2 alpha concen...
OBJECTIVE Prompt post-hypoxia-ischemia (HI) revascularization has been suggested to improve outcome in adults and newborn subjects. Other than hypoxia-inducible factor, sensors of metabolic demand remain largely unknown. During HI, anaerobic respiration is arrested resulting in accumulation of carbohydrate metabolic intermediates. As such succinate readily increases, exerting its biological eff...
In a group of 20 matched primigravid patients labour was induced by forewater amniotomy followed by intravenous oxytocin (Syntocinon) administered in escalating doses. Ten of these patients, in a double-blind trial, also received prostaglandin E(2) infused simultaneously with the oxytocin. In the combined prostaglandin-oxytocin group there was a noticeable reduction in the dosage of oxytocin re...
Colorectal cancer poses a major clinical challenge in the developed world where this disease is common. Recent findings suggest that the prostaglandin E(2), the proinflammatory product of elevated cyclooxygenase-2 activity in colon cancer, stimulates cancer cell growth through a G protein-dependent signaling pathway coupling the prostaglandin EP2 receptor to beta-catenin control. These findings...
Specimens of human rheumatoid and nonrheumatoid synovial lining were maintained in nonproliferative organ culture for 20 hours. The culture fluids were then assayed for prostaglandin E(2) (PGE(2)), thromboxane B(2) (TXB(2)), and 6-keto-prostaglandin F(1alpha) (6-keto-PGF(1alpha)) by specific radioimmunoassay. The presence of each of these substances was confirmed by gas chromatography and mass ...
To investigate the components of the prostaglandin biosynthetic pathway, the characteristics of cyclooxygenase (COX)-1, COX-2, hematopoietic prostaglandin D synthase (hPGDS), microsomal prostaglandin E synthase (mPGES), and thromboxane synthase (TXS) were examined for autopsied cases with small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Autopsied patients (n=120) with lung ...
Orczyk & Behrman (1972) reported experiments in rats that indicated that prostaglandins, acting centrally, may have a role in regulating lutropin secretion from the pituitary. They found that systemically administered indomethacin [I-(Cchlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic a id] blocked ovulation, and this blockade could be overcome by administering lutropin. Later it was found that...
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