The Propagation Rule Compiler (PROP) is a tool developed within the ES-PRIT III project IDEA (Intelligent Database Environment for Advanced Applications). It aims at supporting developers of Chimera applications during schema design and prototyping. PROP consists of two components: the rule compiler as such and an explanation facility. The task of the explanation facility is to graphically illu...

Practical and reliable methods for the objective measure of taste function are critically important for studying eating behavior and taste function impairment. Here, we present direct measures of human gustatory response to a prototypical bitter compound, 6-n-propyltiouracil (PROP), obtained by electrophysiological recordings from the tongue of subjects who were classified for taster status and...

This paper presents the implementation of ARQ-PROP II, a limited-depth propositional reasoner, via the compilation of its specification into an exact formulation using the satyrus platform. satyrus’ compiler takes as input the definition of a problem as a set of pseudoBoolean constraints and produces, as output, the Energy function of a higher-order artificial neural network. This way, satisfia...

BACKGROUND Electrical acupuncture (EA) has been utilized in acute pain management. However, the neuronal mechanisms that lead to the analgesic effect are still not well defined. The current study assessed the intensity [optimal EA (OI-EA) vs. minimal EA (MI-EA)] effect of non-noxious EA on supraspinal regions related to noxious heat pain (HP) stimulation utilizing an EA treatment protocol for a...

Enterprise Architecture (EA) is increasingly being used by large organizations to get a grip on the complexity and inflexibility of their business processes, information systems and technical infrastructure. Although seen as an important instrument to help solve major organizational problems, effectively applying EA seems no easy task. Efficient collaboration between architects and EA stakehold...

In the title salt {systematic name: 4-diphenyl-methyl-1-[(E)-3-phenyl-prop-2-en-1-yl]piperazin-1-ium (2Z)-3-carb-oxy-prop-2-enoate}, C26H29N2(+)·C4H3O4(-), the piperazine ring in the cation adopts a distorted chair conformation and contains a positively charged N atom with quaternary character. The dihedral angle between the mean planes of the phenyl rings of the diphenyl-methyl group is 74.2 (...

A general problem in model selection is to obtain the right parameters that make a model t observed data. If the model selected is a Multilayer Perceptron (MLP) trained with Backpropagation (BP), it is necessary to nd appropriate initial weights and learning parameters. This paper proposes a method that combines Simulated Annealing (SimAnn) and BP to train MLPs with a single hidden layer, terme...

The title compound, tert-butyl-propoxycalix[5]arene, C(70)H(100)O(5)·0.5CH(2)Cl(2), crystallizes as a solvate with two mol-ecules of calix[5]arene in 1,2-alternate conformations and one mol-ecule of dichloro-methane in the asymmetric unit. One tert-butyl group in one of the mol-ecules and two in the other are disordered over two positions with occupancy factors fixed at 0.5917:0.4083, 0.5901:0....

During the past 25 years there has been a controversy regarding the adequacy of Newton’s proof of Prop. 1 in Book 1 of the Principia. This proposition is of central importance because its proof of Kepler’s area law allowed Newton to introduce a geometric measure for time to solve problems in orbital dynamics in the Principia. It is shown here that the critics of Prop. 1 have misunderstood Newto...

PROP-1 gene mutations have been reported as a cause of combined pituitary hormone deficiency. Physical and hormonal phenotypes of affected individuals are variable. We report a 63-year-old female who presented with osteoporosis. She was short, did not enter puberty spontaneously and had primary amenorrhea. Biochemical evaluation revealed secondary hypothyroidism and mixed hyperlipidaemia, while...