1 Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Maryland, United States of America, 2 Graduate Program in Life Sciences, Molecular Microbiology and Immunology Program, University of Maryland, Baltimore, Maryland, United States of America, 3 Department of Microbiology and Immunology, School of Medicine, University of Maryland, Baltimore, Maryla...

A novel method for α-hydroxylation of ketones using substoichiometric amount of iodine under metal-free conditions is described. This method has been successfully employed in synthesizing a variety of heterocyclic compounds, which are useful precursors. α-Hydroxylation of diketones and triketones are illustrated. This strategy provides a novel, efficient, mild and inexpensive method for α-hydro...

Fig. 1: Postcard depicting New York central post office at the beginning of the 20th century (1875-1877) with the shielded eagle of the German Reich Fig. 2: Postcard (1869) of the Kingdom of Serbia depicting prince Milan with a postal employee committed in sorting mail Fig. 3: Postcard (1862) of Hong Kong with Queen Victoria of England depicting a country post office along a medium class lady c...

Diaryliodonium salts are shown to undergo rapid, fluoride-promoted aryl exchange reactions at room temperature in acetonitrile. Aryl exchange is shown to be exquisitely sensitive to the concentration of fluoride ion in solution; fast exchange is observed as the fluoride concentration approaches a stoichiometric amount at 50 mM substrate concentration. The reaction is slowed, but not halted if b...