e14563 Background: Tumor-specific neoantigens are considered as personalized and potential ultimate targets for cancer immunotherapy. Recently, neoantigen vaccines have been designed to train the patient's immune system specifically target kill tumor cells. However, safety efficacy of in pancreatic treatment remain poorly understood. Methods: Personalized peptide were successfully manufactured ...

Energy plays a predominant role in the development of society. With advancements technology and growth society (buildings infrastructures), demand for energy is rapidly increasing. Developing countries typically rely on import fossil fuels capital investments infrastructure to meet their needs. The execution solar PV projects developing currently not being implemented promisingly. Therefore, de...

Despite the outstanding role of mesoscopic structures on efficiency and stability perovskite solar cells (PSCs) in regular (n–i–p) architecture, PSCs inverted (p–i–n) architecture have rarely been reported. Herein, an efficient stable NiOx (mp-NiOx) scaffold formed via a simple low-cost triblock copolymer template-assisted strategy is employed, this mp-NiOx film utilized as hole transport layer...

Copper is a frequently used heavy metal worldwide and known to be an essential micronutrient for most living organisms including plants. However, excessive levels of copper in soil may adversely affect plant growth survival. The continuing introduction soil, e.g., through utilization agrochemicals has raised serious environmental concerns throughout the world. A variety plants have capability e...

In the 5G era, more sensitive information will be transmitted on optical networks. Although modern cryptography could support different security mechanisms in layers, layer has not been paid enough attention but it is also vulnerable to attack by tapping or other methods. The optoelectronic firewall one of promising strategies which can accelerate operating speed within manageable costs employi...

Recent studies show that Graph Neural Networks (GNNs) are vulnerable and easily fooled by small perturbations, which has raised considerable concerns for adapting GNNs in various safety-critical applications. In this work, we focus on the emerging but critical attack, namely, Injection Attack (GIA), adversary poisons graph injecting fake nodes instead of modifying existing structures or node at...

Leishmaniasis is a complex vector-borne disease mediated by Leishmania parasite and strong long-lasting CD4+ Th1 CD8+-T cell immunity required to control the infection. Thus far multivalent subunit vaccines have met this requirement more promisingly. However several full protein sequences cannot be easily arranged in one construct. Instead, new emerging immune-informatics based epitope formulat...

The operational slowness in the execution of direct methods for estimating forage mass, an important variable defining animal stocking rate, gave rise to need with faster responses and greater territorial coverage. In this context, aim study was evaluate a method estimate mass Urochloa brizantha cv. BRS Piatã shaded full sun systems, through proximal sensing applied Simple Algorithm Evapotransp...

Abstract Background Topical infectious are among of global challenges which propelled up with antimicrobial resistances. This scenario compels for drug discovery and development. Herbal formulation is one important struggle in the development purpose overcoming various diseases distressing health care settings. Thus, this study aimed to formulate evaluate herbal cream from leaf methanolic extra...

Cellulose and chitosan with remarkable biocompatibility sophisticated physiochemical characteristics can be a new dawn to the advanced drug nano-carriers in cancer treatment. This study aims synthesize layer-by-layer bionanocomposites from rice straw cellulose encapsulated 5-Fluorouracil (CS-CF/5FU BNCs) using ionic gelation method sodium tripolyphosphate (TPP) cross-linker. Data X-ray Fourier-...