OBJECTIVE To study the incidence and indications for labour induction and study the predictors of failed induction. MATERIAL AND METHOD A hospital based prospective study done over a 12 month period between 1st November 2007 to 30th October 2008. SELECTION CRITERIA Singleton pregnancies beyond 37 weeks with vertex presentation and unscarred uterus requiring induction of labour. RESULTS Th...

Premature Rupture of Membranes (PROM) is defined as rupture of membranes prior to onset of labor. It can occur at any gestational week. PROM greater than 24 hours is referred as prolonged PROM and carries risk of ascending infection (1). PROM occurs in 8%-10% of all term pregnancies and in 2%-4% of all preterm singleton pregnancies (1,2). The most important maternal risk is intrauterine infecti...

Objective: Evaluation of fetal and maternal outcomes in pregnancy with leiomyoma uteri. Methods: Total 50 pregnant women with uterine myoma attending the department of Obstetrics and Gynecology of IPGME&R, Kolkata were followed during the antenatal, intranatal and postnatal period. Total 200 women of normal uncomplicated pregnancy were recruited as control and matched for age and parity. Result...

BACKGROUND Since 2006, the empiric use of azithromycin in women at risk of premature birth has become prevalent in our institution without any evidence of its efficacy. Although antibiotics can prolong pregnancy in preterm prolonged rupture of membranes, no published data are available for women with intact membranes. OBJECTIVES To describe the purpose of adding azithromycin to the usual trea...

A 32-year-old Caucasian woman of body mass index (BMI) 46 presented with urinary symptoms to accident and emergency (A&E). Acute pyelonephritis was the diagnosis. Transabdominal scan revealed a live term fetus. Both the partners were unaware of the ongoing pregnancy until diagnosed. She underwent emergency cesarean under general anaesthesia (GA) for nonreassuring CTG, severe chorioamnionitis, a...

OBJECTIVE The aim of this study was to determine the value of detecting insulin-like growth factor binding protein-1 (IGFBP-1) in the cervical-vaginal secretion in the prediction of delivery in women with clinically uncorfirmed preterm premature rupture of membranes (PPROM). MATERIAL AND METHODS A total of 87 women, gestational age between 20 and 36 weeks were enrolled into this prospective s...

BACKGROUND In this study, we aimed to investigate the expression of NOD-like receptor protein 3 (NLRP3) and caspase-1 in fetal membrane and placental tissues of patients with premature rupture of membrane (PROM), and to explore their role in PROM. MATERIAL AND METHODS Ninety women participated in this study: a control group of 30 healthy pregnant women, 30 with PPROM, and 30 with TPROM. Immunoh...

Objective: To study the determinants and outcome of prelabour rupture of membrane at term pregnancy in Patan Hospital. Method: A prospective, hospital based case control study done in maternity ward of Patan Hospital over the period of three months (Poush 2059-Phalgun 2059). A total no of 100 pregnant women with prelabor rupture of membrane and 100 pregnant women without prelabor rupture of mem...