Photodynamic therapy has been developed as an alternative therapy of cancer. The aim of this study was to examine whether PDT with hexenyl ester of 5-aminolaevulinic acid (ALA-hx) inhibits the proliferation of the salivary gland adenocarcinoma SGT cells. Cell proliferation was examined by MTT assay. The gene expression of Coproporphyrinogen oxidase (CPO) and ROS production was also examined. Fl...

Objective(s): Umbilical cord blood is a good source of the mesenchymal stem cells that can be banked, expanded and used in regenerative medicine.  The objective of this study was to test whether amniotic membrane extract, as a rich source of growth factors such as basic-fibroblast growth factor, can promote the proliferation potential of the umbilical cord mesenchymal stem cells. Materials and ...

Introduction This study aimed to investigate the biological role of microRNA 93 (miR-93), a novel tumor-related miRNA, in human hepatocellular carcinoma (HCC) and elucidate potential molecular mechanisms involved. Material methods Quantitative real-time polymerase chain reaction (qRT-PCR) was conducted determine expression miR-93 HCC tissues cell lines. The log-rank test Kaplan-Meier survival a...

Aberrant proliferation and migration of residual lens epithelial cells (LECs) is the main cause posterior capsule opacification (PCO) after cataract surgery. The purpose this study was to confirm protective effects Astragaloside IV (AST) in transforming growth factor beta (TGF-β)-induced LECs. Human LECs, SRA01/04, were used study. MTT assay EdU perform cell viability proliferation, respectivel...

Background and Objectives The imperative role of dental pulp stem cells (DPSCs) in regenerative therapy demands an in-vitro expansion which must deal with the safety and ethical problems associated with fetal bovine serum (FBS). The primary aim of this study was to compare the effects of human platelet rich fibrin (hPRF) exudate Vs FBS on proliferation and osteodifferentiation of human dental p...

Artemisinin and its derivatives are very important new class of antimalarial drugs. One of the most important artemisinin derivatives is artemether. The antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. The aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. I...

Artemisinin and its derivatives are very important new class of antimalarial drugs. One of the most important artemisinin derivatives is artemether. The antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. The aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. I...

Soybean bioactivity is significantly enhanced during tempeh fermentation. This study aimed to evaluate the efficacy of on colorectal cancer cells in vitro and colon precancerous lesions (aberrant crypt foci, ACF) vivo. In assay, water extract (WET) could inhibit proliferation Caco-2 cells. animal assay using 1,2-dimethylhydrazine (DMH)-induced Sprague–Dawley (SD) rats, 12-weeks daily feeding de...

Chemical investigation of Garcinia eugenifolia and Calophyllum enervosum yielded six compounds. One of these was found to be a novel compound identified as enervosanone. Five known compounds cambogin, epicatechin, osajaxanthone, rubraxanthone and isocowanol, were also isolated. These compounds were tested for their bioactivity as antimicrobial, antioxidant and cytotoxicagents. Antimicrobial...

the effects of mobile phone exposure on humans, due to its potential health hazards, have become the focus of interest since many years ago. the effect of global system for mobile communications (gsm 900 mhz) on growth and proliferation rate of mesenchymal stem cells was assessed at the different distances and intensities of radiation. a subscriber identity module (sim) card was inserted to thi...