Prognostic factors are essential for patient management and counseling. Most cancer patients receive treatment based on the presence or absence of several risk factors. The most prominent example of this is tumor, node, metastasis staging, but many diseases are moving beyond the simple one-sizefits-all stage classification and using stylized prognostic factors. A notable difficulty in the devel...

OBJECTIVE To determine appropriate counseling of patients with olfactory dysfunction. DESIGN Retrospective analysis. SETTING Interdisciplinary Center for Smell and Taste, University of Dresden Medical School, Technical University of Dresden. PATIENTS A total of 361 males and 533 females, aged 11 to 84 years, who twice reported to the Interdisciplinary Center for Smell and Taste. MAIN OU...

BACKGROUND AND OBJECTIVES Pulmonary hypertension is a hemodynamic and pathophysiological condition defined as an increase in mean pulmonary pressure more than or equal to 25 mm Hg. Evaluation of pulmonary hypertension severity and prognosis plays a central role in the management of these patients, between diagnosis and therapeutic decision making. The aim of our study was to identify the advers...

background: the aim of this study was to detect prognostic factors in recurrent breast cancer metastasis. materials and methods: th is retrospective cohort study employed data from 996 breast cancer patients of isfahan seyed-o-shohada research center from 1998 to 2010. stratifi ed cox proportional hazards model, marginal approach, was used to evaluate the prognostic value of estrogen receptor, ...

Background: Reduced survival and impaired quality of life of the children affected by cancers is one of the most important health problems. In this study, 5-year survival of children affected with Central nervous system (CNS) tumors and its related factors were evaluated. Materials and Methods: Participants in this historical cohort study consisted of 161children with mean age of diagnosis 72 ...

OBJECTIVES To determine prognostic factors for mortality in neonates with tetanus and to assess the associations between prognostic factors and neonatal tetanus (NT) mortality. METHODS Five databases were searched for studies on prognostic factors and NT mortality published up to April 2013 to identify studies relevant to this review. Prognostic factors of interest were birth weight, age at o...

Pancreatic cancer is a frequent and lethal disease ranking fourth as a cause of cancer-related death in Western countries. There are patients, though, who respond well to chemotherapy and have a prolonged survival. There is an effort towards identification of specific characteristics of these tumor cells in order to identify those patients who will benefit from chemotherapy and use them as prog...

Colorectal cancer (CRC), the most common gastrointestinal cancer, causes around 2500 deaths annually in Sweden. Tumour resection is still the only curative treatment, but surgery is successful in only about half of the patients. The best prognostic factor so far is the tumour stage according to the TNM classification system which is based on the perioperative findings of the extent of the tumou...

Standardized gynecological oncological therapeutical guidelines are based on ordinary predictive factors, such as depth of stromal invasion, histopathological type of tumor, lymphovascular space invasion, lymph node metastases. Unfortunately, the power of these prognostic factors is not able to determine the safety of this procedure in the relation to disease recurrence in a group of patients w...

A major issue in the analysis of diseases is the identiication and assessment of prognostic factors relevant to the development of the illness. Statistical analyses within the proportional hazards framework suuer from a lack exibility due to stringent model assumptions such as additivity and time{constancy of eeects. In this paper we use tree based models and varying coeecient models to allow f...