Fibroblasts from young patients exhibiting clinical features of progeroidal syndromes showed decreased biosynthesis of the small proteoglycan decorin. Cells in culture were metabolically labeled, and proteoglycans secreted into the medium were analyzed electrophoretically after immunoprecipitation with antibodies raised against decorin and biglycan. Fluorograms showed regularly a reduction to 1...

We present a comparison of a text-driven and a speech driven visual speech synthesiser. Both are trained using the same data and both use the same Active Appearance Model (AAM) to encode and re-synthesise visual speech. Objective quality, measured using correlation, suggests the performance of both approaches is close, but subjective opinion ranks the text-driven approach significantly higher.

In this study, we present a new multi-band image representation for improving AAM segmentation accuracy for illumination invariant face alignment. AAM is known to be very sensitive to the illumination variations. We have shown that edges, originating from object boundaries are far less susceptible to illumination changes. Here, we propose a contour selector which mostly collects contours origin...

BACKGROUND Alteration in the immune system is one of the most profound aspects of aging. Progressive changes in the number of B lymphocyte progenitors during aging have been reported but the underlying mechanisms are still elusive. A heterozygous G608G mutation in the LMNA gene leads to a deletion of 50 amino acids in lamin A protein, termed progerin, and is the predominant cause of Hutchinson-...