objective(s): yu-ping-feng-san (ypfs) is a classical traditional chinese medicine that is widely used for treatment of the diseases in respiratory systems, including chronic obstructive pulmonary disease (copd) recognized as chronic inflammatory disease. however, the molecular mechanism remains unclear. here we detected the factors involved in transforming growth factor beta 1 (tgf-β1)/smad2 si...

BACKGROUND Few valid, disease-specific measures of health-related quality of life (HRQOL) capture the spectrum of symptoms associated with Huntington's disease (HD). The HD-PRO-TRIAD™ is a new, HD-specific, patient-reported outcome (PRO) instrument of the HD symptom triad (cognitive decline, emotional/behavioral dyscontrol, and motor dysfunction) designed for clinical research and practice. The...

BACKGROUND Gastroparesis (Gp) is a poorly understood chronic gastrointestinal medical condition for which patient reported outcomes (PRO) are lacking. Previously developed symptoms scoring has been used for several decades. Using symptoms scores as a basis for documentation, 12 years of support/focus group patient feedback from the nearly 1000 attendees were integrated with medical care and rec...

The Embryo Rescue Case asks us to consider whether we should save a fully-developed child or tray full of many embryos from fire. Most people pick the child. This allegedly provides evidence against view that have same moral status as developed humans. Pro-life philosophers usually grant you child, but say this doesn’t undermine claim possess status. There may be reasons besides differing Meanw...

Cocoa is thought to be an excellent source of antioxidants. Here, we investigated the effects of cocoa supplementation on Drosophila melanogaster life span under different oxidative stress conditions. Our results illustrate that a moderate supplementation of cocoa under normoxia increases the average life span, whereas, at higher concentrations, average life span is normal. Under hyperoxia or i...

Heparin-induced thrombocytopenia paradoxically is a transient pro-thrombotic disorder triggered by heparin exposure. If not treated appropriately, it can be life threatening because of its related thromboembolic complications. In particular, it presents a unique challenge in patients needing extracorporeal life support, because anticoagulation is essential for safe management. This case report ...

Praised for its revolutionary technique and studied for its perplexing imagery, Jan van Eyck’s Arnolfini Portrait has remained a riddle since the 19th century. Completed in 1434 in Bruges, the work showcases a skilled use of oil paints and impressively realistic details. More famous and perhaps more important, however, than van Eyck’s technique are the two figures and the objects which decorate...

Will reading habit influence your life? Many say yes. Reading measurement of pro c type natriuretic peptide in plasma technical briefs is a good habit; you can develop this habit to be such interesting way. Yeah, reading habit will not only make you have any favourite activity. It will be one of guidance of your life. When reading has become a habit, you will not make it as disturbing activitie...

Two studies examined misperceptions of disagreement in partisan social conflicts, namely, in the debates over abortion (Study 1) and politics (Study 2). We observed that partisans tend to exaggerate differences of opinion with their adversaries. Further, we found that perceptions of disagreement were more pronounced for values that were central to the perceiver’s own ideology than for values th...