نتایج جستجو برای: primordial follicles

تعداد نتایج: 22985  

2011
José Ricardo de Figueiredo Ana Paula Ribeiro Rodrigues Valdevane Rocha Araújo

Background: The majority of thousands of oocytes in the ovaries are small, non-growing and reside in preantral follicles (PFs). The development of a culture system for preantral follicle may be very useful for understanding the complex mechanism in folliculogenesis at early stages of development as wells as could offer a significant way for the propagation of livestock, including goats. This pa...

2015
Wei-Juan Liu Xing-Mei Zhang Na Wang Xiao-Ling Zhou Yu-Cai Fu Li-Li Luo

BACKGROUND Silent information regulator 2 related enzyme 1 (SIRT1) is one of the key factors in the mechanism of calorie restriction (CR) extending lifespan of animals. The aim of the study is to investigate if CR prolongs ovarian lifespan in mice through activating SIRT1 signaling. METHODS In the present study, 21 female C57BL/6 mice were divided into three groups: the control (n = 7), CR (n...

2013
Shabnam Abdi Mojdeh Salehnia Saman Hosseinkhani

BACKGROUND The aim of this study was to investigate follicular growth and steroid production in neonatal mouse ovary during in vitro culture. MATERIALS AND METHODS In this experimental study, 7-day-old mouse whole ovaries were cultured in α-MEM (medium supplemented with 100 mIU/ml recombinant follicle stimulating hormone, 1% insulin, transferrin and selenium (ITS), 5% fetal bovine serum (FBS)...

Journal: :Gynecologic and obstetric investigation 2013
Atunga Nyachieo Carl Spiessens Daniel C Chai Nicholas M Kiulia Dorien Willemen Jason M Mwenda Claire Bourgain Thomas M D'Hooghe

BACKGROUND Ovarian tissue cryopreservation by vitrification is an attractive technique for fertility preservation in women. However, this technique has not been optimized. The aim of this study was to evaluate the baboon as a model for the preclinical study of ovarian tissue cryopreservation by vitrification and thawing. METHODS Ovarian cortical tissues (1-mm cubes) were obtained surgically f...

Journal: :The Kurume medical journal 2007
Go Matsuo Kimio Ushijima Atsuhiko Shinagawa Syun-Ichi Takahashi Naoki Fujiyoshi Syuji Takemoto Atsumu Terada Akimasa Fukui Toshiharu Kamura

To reduce chemotherapy induced gonadotoxicity, co-treatment with gonadotropin releasing hormone against analogue (GnRHa) was tested using rat model. Leuprorelin acetate (Leuplin) with or without cisplatin (CDDP) was given subcutaneously at a dose of 9.4 microg/ml to Wistar strain female rats. The total number of follicles was counted and the maturation of follicles was evaluated at the largest ...

2007
Tom Kelsey

We report on the use of AI techniques – including image analysis, feature recognition, machine learning and constraint satisfaction – applied to the problem of determining the population of primordial follicles in a human ovary. We highlight the importance of accurate population data for studies that aim to predict the age of menopause in healthy women, and for studies that quantify damage to o...

Journal: :The Onderstepoort journal of veterinary research 2006
M C Madekurozwa W H Kimaro

The ultrastructure of the follicular wall in primordial, previtellogenic and vitellogenic follicles of the sexually immature ostrich is described in the present study. The follicular wall consists of a zona radiata, granulosa cell layer, basal lamina and thecal layer. Cytoplasmic processes from the plasma membranes of the granulosa cell layer and the ovocyte form the zona radiata in previtellog...

Journal: :Reproduction, fertility, and development 2014
Silvia C Modina Irene Tessaro Valentina Lodde Federica Franciosi Davide Corbani Alberto M Luciano

High-producing dairy cows are subfertile; however, the mechanisms responsible for the decreased fertility are unknown. The aim of the present study was to test the hypothesis that culled dairy cows (4-8 years old) characterised by 'Lo' ovaries (i.e. those with <10 mid-antral follicles) are affected by premature ovarian senescence. Cows in which both ovaries were 'Lo' ovaries represented 5% of t...

Journal: :Fertility and sterility 2002
Banu Demirci Bruno Salle Lucien Frappart Michel Franck Jean François Guerin Jacqueline Lornage

OBJECTIVE To evaluate DNA fragmentation in the oocyte of primordial and primary follicles and morphology of these follicles after freezing and thawing of ovarian cortex in sheep using two freezing protocols. DESIGN Fragmentation of DNA was evaluated by the terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end-labeling (TUNEL) technique. SETTING Fertility clinic in a large univ...

Journal: :Nanoscale 2014
Dimple A Modi Suhair Sunoqrot Jason Bugno Daniel D Lantvit Seungpyo Hong Joanna E Burdette

Ovarian cancer is the most lethal gynecological malignancy. Current treatment modalities include a combination of surgery and chemotherapy, which often lead to loss of fertility in premenopausal women and a myriad of systemic side effects. To address these issues, we have designed poly(amidoamine) (PAMAM) dendrimers to selectively target the follicle stimulating hormone receptor (FSHR), which i...

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