Previous studies have shown that thyroid hormone directly stimulates bone resorption in in vitro organ culture, and in adults excess thyroid hormone is associated with decreased bone mineral density. There are limited data in children regarding the effect of hyperthyroidism on bone metabolism and even fewer instances in the literature of hyperthyroidism presenting with bone demineralization and...

Successful healing of a nine-year tibial nonunion resistant to six previous surgical procedures was achieved by tissue engineering. We used autologous bone marrow stromal cells (BMSCs) expanded to 5 x 10(6) cells after three weeks' tissue culture. Calcium sulphate (CaSO4) in pellet form was combined with these cells at operation. The nonunion was clinically and radiologically healed two months ...

IN the fourth year since its inception in 1959 the Mycological Laboratory of the Department of Microbiology, Queen's University of Belfast, continued to provide a diagnostic service for the isolation and/or identification of fungi associated with human sources. During 1962 inycological examinations were made on 1,322 specimens fromn 1,000 patients from thirty hospitals, clinics or laboratories,...

Tuberculosis of the extra-oral region is uncommon and is rarely primary. Extra-oral involvement of the cheek in the absence of tuberculosis elsewhere in the body is rare. To the best of our knowledge, we report here the first case of primary tuberculosis of the cheek in a 31-year-old male presenting as a nodular swelling of the cheek. Previous reported cases of extra-oral involvement of the che...

David Benet had problems to solve when he came in to lead the highest-growth unit at a large medical devices company. Although sales had increased when two new products launched the previous year, the numbers still fell short of expectations, given all the evidence of unmet customer needs. The company’s future hinged on the success of both products—an instrument for inserting stents into blocke...

A 22 year old male referred with palpitation. General appearance and physical exam impressed us in that the patient has Marfan syndrome. Cardiac catheterization showed diffuse arterial ectasia. We found no previous report of this generalized diffuse ectasia.

A new method to measure nonlinear dependence between two variables is described using mutual information to analyze the separate linear and nonlinear components of dependence. This technique, which gives an exact value for the proportion of linear dependence, is then compared with another common test for linearity, the Brock, Dechert and Scheinkman (BDS) test. Copyright c © 0000 John Wiley & So...

This paper introduces a new type of intranet – the compliance intranet – and describes its socio-technical shaping. Compliance intranets serve to enforce industry standards, to measure the performance of a company against industry or governmentally established standards, or to establish standards within the organization or within a larger domain. These intranets may be quality management system...

In a survey we found that most developers have experienced duplicated bug reports, however, only few considered them as a serious problem. This contradicts popular wisdom that considers bug duplicates as a serious problem for open source projects. In the survey, developers also pointed out that the additional information provided by duplicates helps to resolve bugs quicker. In this paper, we th...