BACKGROUND AND OBJECTIVES Teaching about evidence-based medicine (EBM) is widespread, yet physicians still use rapid references preferentially over EBM techniques such as literature searching and appraisal of original research. The Internet now provides rapid access to preappraised evidence. We provided clinically integrated teaching of using the Internet to answer clinical questions for third-...

We consider a finite population mixed model that accommodates response errors and show how to obtain optimal estimators of the parameters in pretest-posttest context. illustrate method with estimation difference gain between two interventions simulation study compare empirical version proposed estimator (obtained by replacing variance components estimates) obtained via covariance analysis usual...

BACKGROUND To examine the extent to which state adoption of the Centers for Disease Control and Prevention (CDC) 2006 revisions to adult and adolescent HIV testing guidelines is associated with availability of other important prevention and medical services. We hypothesized that in states where the pretest counseling requirement for HIV testing was dropped from state legislation, substance use ...

S c e n a r i o On inpatient teaching rounds, we recently discussed the admission of a 45-year-old woman with chest pain. This patient presented to the emergency department after an episode of chest pain lasting approximately 30 minutes. The pain was pleuritic in nature, located on the right side of her chest, and was associated with shortness of breath. The patient reported no palpitations, di...

BACKGROUND The AMPLICOR assay (Roche; Branchburg, NJ), a rapid direct amplification test for Mycobacterium tuberculosis, has only been licensed for use in smear-positive respiratory specimens. However, many patients with pulmonary tuberculosis (PTB) have smear-negative disease. The clinical utility of this test in patients with smear-negative PTB is unknown. OBJECTIVE To evaluate the effect o...

OBJECTIVE This study examined the efficacy of computed tomographic angiography (CTA) for detection of ruptured and unruptured aneurysms after adjustment for their size distributions under various conditions of aneurysm prevalence. METHODS A systematic review was used to estimate 1) the aneurysm size-specific sensitivity and specificity of CTA, and 2) the size distributions of ruptured and unr...