It has been established that inhaled tobramycin has a positive effect on respiratory function in Pseudomonas-aeruginosa positive patients with cystic fibrosis (CF). In a previous study the authors reported that low-dose tobramycin preparations containing the preservative phenol caused significant bronchial obstruction. Recently, high-dose tobramycin preparations with and without preservatives/p...

An ion-interaction high-performance liquid chromatography (HPLC)-diode-array detection method is developed and optimized for the separation of typical antimicrobial agents used in cosmetics and hygiene products. The most used preservatives contain different molecular structures, different functionalities, and are characterized by different chemical properties. Organic acids, alkyl esters of ben...

There is growing concern about food safety and especially about inputs of pathogenic microorganisms with possible implications for human health and the environment [Duniere et al., 2011]. Microbial activity is a primary mode of deterioration of many foods and is often responsible for the loss of quality and safety. Concern over pathogenic and spoilage microorganisms in foods is increasing due t...

the usage of antimicrobial materials for coating meat products, in addition to reducing the microbial population and increase of the quality safety of products, be greatly reduced usage of nitrites as preservatives and synthetic carcinogens. compounds that have antimicrobial activity can be mixed, stabilized or incorporated with edible coatings. spices and vegetable extracts are also a group of...

In this study, Cu, Ag, and Fe nanoparticles (NPs) are used in shampoo, hand washing liquid (HWL) and dish washing liquid (DWL) instead of the conventional synthetic preservatives such as isothiazolinones; since the latter often act as potent sensitizers that leads to development of allergic contact dermatitis. The above NPs are considerably effective against Escherichia coli and Staphylococcus ...

Preservative treatment of wood has a long history in the United States and throughout the world. Even the early settlers to the New World in the 17th century used wood preservatives to protect homes and other structures. The treated wood industry in the United States is evolving as new products emerge, technology advances, and environmental concerns increase. Recently, chromated copper arsenate...

The aim of the work was to quantify possible interactions between surfactants and preservatives, comparing surface properties, in model pharmaceutical formulations. Surface parameters of 2-component surfactant-preservative aquous mixtures were determined with a Wilhelmy plate technique, for the so-called principal surfactants (polysorbate 80, egg lecithin, phosphatidylcholine) and preservatives...

Contact dermatitis due to cosmetic products is a common dermatologic complaint that considerably affects the patient's quality of life. Diagnosis, treatment, and preventive strategies represent a substantial cost. This condition accounts for 2% to 4% of all visits to the dermatologist, and approximately 60% of cases are allergic in origin. Most cases are caused by skin hygiene and moisturizing ...

A simple and sensitive method was developed for the analysis of preservatives sodium benzoate, methylparaben and propylparaben in nystatin suspensions by reversed-phase high performance liquid chromatography (HPLC), equipped with a C18 column and PDA detector. The mobile phase was a mixture of acetonitrile and acetate buffer of pH 4.4 (35:65 v/v). Under the optimized experimental conditions, se...

Preservation of foods by natural and microbiological methods may be a satisfactory approach solving economic losses due to microbial spoilage of raw materials and food products, to reduce the incidence of food borne illnesses, and to meet the food requirements of the growing world population. Since many people are concerned about the safety of chemical preservatives are questioned with regard t...