Presbycusis is one of the most prevalent neurodegenerative diseases of aging caused by changes in peripheral (cell loss in organ of Corti, spiral ganglion and stria vascularis) and central auditory systems (consequent to peripheral modifications or due to changes in the neurobiologic activity underlying central processing of auditory informations) [1]. Consequences are reduced sensitivity, tuni...

Abstract Introduction One in six adults are affected by hearing loss, and this number increases with age.(1) Inadequate communication is a barrier to the delivery of effective care for people loss.(2) Communication regarding medicines particularly relevant pharmaceutical older who more likely be living have multiple comorbidities experience polypharmacy, risk factor adverse drug events. This st...

With advancements in modern medicine and significant improvements in life conditions in the past four decades, the elderly population is rapidly expanding. There is a growing number of those aged 100 years and older. While many changes in the human body occur with physiological aging, as many as 35% to 50% of the population aged 65 to 75 years have presbycusis. Presbycusis is a progressive sens...

Aging has been associated with oxidative stress and the accumulation of mitochondrial DNA (mtDNA) mutation. The previous study has established a mimetic rat model of aging using D-galactose (D-gal) and revealed that chronic injection of D-gal can increase NADPH oxidase (NOX)-dependent oxidative stress, mitochondrial damage and apoptosis in the peripheral auditory system. However, the effects of...

Bilateral vestibulopathy is a condition with vestibular hypofunction of both inner ears. Patients this diagnosis will often complain dizziness and/or imbalance in darkness and when walking uneven terrain also experience oscillopsia. Predominant etiology idiopathic. A 73-year old man complaints for 2 days. Objective findings included spontaneous nystagmus, positive Romberg test eyes closed, path...