A population of reticulospinal neurons with short latency response to startle-inducing stimuli was identified in the nucleus reticularis pontis caudalis (NRPC) and nucleus gigantocellularis (NRGC) of the medial pontomedullary reticular formation. The threshold and magnitude of response to auditory stimuli was correlated in these cells and in the muscles mediating startle. Startle-related neuron...

Cognitive function studied in animal models of schizophrenia Cognitive dysfunction is considered a core deficit of schizophrenia, which currently lacks effective pharmacological treatment. In order to identify novel and more effective drug treatments, translational experimental animal models of cognitive dysfunction are required. Schizophrenia-like symptoms can be induced in humans by phencycli...

• hnRNPLL is abundantly expressed in immune memory T lymphocytes and the brain. hypomorphism thunder mice ( hnrpll ) causes cell deficits. show enhanced tail suspension immobility reduced learning/memory. subtle prepulse intensity-related inhibition. No changes forced swim test, plus-maze, startle or exploratory habituation. Heterogeneous nuclear ribonuclear protein l -like (hnRNPLL) an RNA bin...