A popular theory for why firms take nonprofit status is that it is a signal of quality. This paper offers a simple, empirical test of this theory. If nonprofit status signals quality, surely nonprofit firms would want to ensure that consumers are aware of this. A natural way for firms to do this is to indicate their nonprofit status in their advertising. Taking this cue, we conducted a survey o...

Catalytic osmylation of cis and trans 2-cyclohexene-cyclohexanol (1a) and (1b) are carried out in the presence of N-methyl morpholine-N-oxide. Under the same conditions, only the cis isomer reacted, leading to triol (3). The steric hindrance of the equatorial OH group probably prevents the trans isomer from entering into such reaction. Triol (3) was also obtained from the reduction of the d...

A photolabile azido derivative of the kaurene oxidase inhibitor 1-(4-chlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-l-yl) pentan-3-ol (paclobutrazol) has been synthesized for use as a photoaffinity labeling agent. The compound was tested as an inhibitor of the oxidation of ent-kaurene catalyzed by cell-free preparations from endosperm of Cucurbita maxima. The I(50) of the azido derivative was 9.5 ...

A thymidine analog, 5-ethynyl-2'-deoxyuridine (EdU), has been reported as a rapid labeling tool for direct measurement of cells in S-phase. The alkynyl group of EdU is a biologically inert group that undergoes an extremely selective reaction with azido-functionalized groups via Cu(I)-catalyzed alkyneazide cycloaddition (CuAAC or "click") reaction. Here we report the highly efficient reaction of...

The potential of E–Z photoisomerization in molecular organic light-to-thermal conversion and storage an E–styryl merocyanine system was studied a polar acidic medium. A photoswitchable styryl dye (E)-2-(2-(2-hydroxynaphthalen-1-yl)vinyl)-3,5-dimethylbenzo[d]thiazol-3-ium iodide synthesized for the first time. reversible photoisomerisation investigated using UV-Vis spectroscopy DFT calculations....

A series of novel 3-(prop-1-en-2-yl)azetidin-2-one, 3-allylazetidin-2-one and 3-(buta-1,3-dien-1-yl)azetidin-2-one analogues combretastatin A-4 (CA-4) were designed synthesised as colchicine-binding site inhibitors (CBSI) in which the ethylene bridge CA-4 was replaced with a β-lactam (2-azetidinone) scaffold. These compounds, together related prodrugs, evaluated for their antiproliferative acti...