Lineal (poloxamers or Pluronic®) or X-shaped (poloxamines or Tetronic®) amphiphilic tri-block copolymers of poly(ethylene oxide) and poly(propylene oxide) (PEO-PPO-PEO) have been broadly explored for controlled drug delivery in different regenerative medicine approaches. The ability of these copolymers to self-assemble as micelles and to undergo sol-to-gel transitions upon heating has endowed t...

Calculations of the conformational preferences of isolated single chains of poly(2,6-dimethylphenylene oxide) (PPO) and bisphenol-A polycarbonate (PC) predict that the rings of both chains are nearly free rotors a t room temperature. However, experimental dipolar rotational spin-echo 13C NMR shows that in the glass, the rings of PPO execute only small-amplitude motions while those of PC undergo...

Polyphenoloxidase (PPO; EC 1.14.18.1) extracted from Mentha arvensis leaves was isolated by (NH4)2SO4 precipitation and extensive dialysis. Its optimum pH and temperature varied with the substrate. The PPO showed activity with various diphenols. Km values were found 0.825, 0.928 and 7.41mM for caffeic acid, 4-methylcatechol and catechol, respectively. On heat-inactivation, half of the activity ...

Peach cultivars contribute to unique product characteristics and may affect the degree of browning after high-pressure processing (HPP). Nine peach cultivars were subjected to HPP at 0, 100, and 400 MPa for 10 min. Proton nuclear magnetic resonance (1H NMR) relaxometry, light microscopy, color, polyphenol oxidase (PPO) activity, and total phenols were evaluated. The development of enzymatic bro...

Policy Commercial Members: Managed Care (HMO and POS), PPO, and Indemnity Medicare HMO Blue and Medicare PPO Blue Members Genetic tests for the screening, detection, and management of prostate cancer are INVESTIGATIONAL. This includes, but is not limited to the following:  Single-nucleotide polymorphisms (SNPs) for risk assessment, or  PCA3 for disease diagnosis and prognosis, or  TMPRSS fus...

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We propose a new family of policy gradient methods for reinforcement learning, which alternate between sampling data through interaction with the environment, and optimizing a “surrogate” objective function using stochastic gradient ascent. Whereas standard policy gradient methods perform one gradient update per data sample, we propose a novel objective function that enables multiple epochs of ...

Several vegetables and vegetable residues were used as sources of enzymes capable to discolor indigo carmine (IC), completely or partially. Complete discoloration was achieved with aqueous extracts of green pea seeds and peels of green pea, cucumber, and kohlrabi, as well as spring onion leaves. The source of polyphenol oxidase (PPO), pH, time, and aeration is fundamental for the discoloration ...

Two platinum(II) terpyridyl-based metallo-supramolecular triblock copolymers, [ClPt(tpy)PEO-PPO-PEO(tpy)PtCl](OTf)(2) (1) and [(Ph-C≡C)Pt(tpy)PEO-PPO-PEO(tpy)Pt(C≡C-Ph)](OTf)(2) (2), have been synthesized and characterized. The two complexes were found to aggregate with PtPt and/or π-π interactions at high temperature, which have not been reported so far, as revealed by UV/Vis absorption, emiss...

is an open access repository that collects the work of Arts et Métiers ParisTech researchers and makes it freely available over the web where possible. Abstract-This paper describes the specifications of an interoperability platform based on the PPO (Product Process Organization) model developed by the French community IPPOP in the context of collaborative and innovative design. By using PPO mo...