We outline the basic features of a spectral multidomain penalty method (SMPM)based solver for the pressure Poisson equation (PPE) with Neumann boundary conditions, as encountered in the time-discretization of the incompressible Navier-Stokes equations. One one hand, the SMPM discretization enables robust under-resolved simulations without sacrificing high accuracy. On the other, the solution of...

Nonalcoholic fatty liver disease (NAFLD) is caused by ectopic fat accumulation in the liver. NAFLD is associated with hepatic inflammation and oxidative stress, resulting in nonalcoholic steatohepatitis (NASH) with advanced fibrosis. Placental extracts have been used to treat various chronic diseases due to their antioxidative effect. However, the effects of the extracts on the development of N...

The use of amikacin (AMK) in present treatment strategies results in severe ototoxicity; however, the underlying molecular mechanisms of this toxicity remain unclear. In this study, we investigated the effectiveness of orally administered pomegranate peel extract (PPE), a strong antioxidant, as a protective agent against AMK-induced ototoxicity. To this end, PPE was orally administered to adult...

introduction poultry meat enriched with long-chain polyunsaturated fatty acids n-3 (pufa lc n-3) can make a nutritionally meaningful contribution to western diets in which consumption of pufa lc n-3 is low. enrichment of poultry meat with this fatty acid is usually achieved by inclusion of fish oil in broiler diet (23, 24). however, meat enriched in this way is susceptible to quality deteriorat...

OBJECTIVES Firefighters are exposed to hazardous conditions as a result of their occupation and often understand the dangers of these toxic exposures; yet, it remains unclear why some refrain from wearing personal protective equipment (PPE) in dangerous situations. We were intrigued by the gap between demonstrated safety knowledge and lack of connection to observed or self-reported safety behav...

INTRODUCTION The outcome of total hip (THA) and knee arthroplasty (TKA) may be optimised through preoperative patient education (PPE). It is hypothesised that PPE reduces anxiety, ensures realistic patient expectations and enhances post-operative outcome. The objective was to determine whether the literature supports a positive effect of PPE on post-operative outcomes including anxiety, pain, l...

The PE and PPE proteins first reported in the genome sequence of Mycobacterium tuberculosis strain H37Rv are now identified in all mycobacterial species. The PE-PPE domain (Pfam ID: PF08237) is a 225 amino acid residue conserved region located towards the C-terminus of some PE and PPE proteins and hypothetical proteins. Our in-silico sequence analysis revealed that this domain is present in all...

The Planar cell Polarity Effector (PPE) genes inturned, fuzzy, and fritz are downstream components in the frizzled/starry night signaling pathway, and their function is instructed by upstream Planar Cell Polarity (PCP) core genes such as frizzled and dishevelled PPE proteins accumulate asymmetrically in wing cells and function in a protein complex mediated by direct interactions between In and ...

The inhibitory function of alpha 1 antitrypsin (alpha 1AT) has been studied in the lung secretions of 31 patients with chronic obstructive bronchitis. The inhibitory capacity for a single sample showed a wide range (median 0.13 micrograms porcine pancreatic elastase (PPE) inhibited per microgram alpha 1 antitrypsin; range 0-0.55 micrograms), and all but five of 86 samples studied were capable o...