نتایج جستجو برای: ppara
تعداد نتایج: 391 فیلتر نتایج به سال:
Fatty acids bound to albumin are filtered through glomeruli, reabsorbed by proximal tubular epithelial cells, and metabolized. Because albumin serves as a carrier, an increase in delivery of fatty acids to the proximal tubule may occur in proteinuric states, possibly leading to toxic effects. At present, the contribution of fatty acids to tubulointerstitial damage and the mechanisms underlying ...
UNLABELLED Athletic performance is a polygenic trait influenced by both environmental and genetic factors. OBJECTIVE To investigate individually and in combination the association of common gene polymorphisms with athlete status in Ukrainians. METHODS A total of 210 elite Ukrainian athletes (100 endurance-oriented and 110 power-orientated athletes) and 326 controls were genotyped for ACE I/...
The liver fluke, Fasciola hepatica (F. hepatica), is a common parasite of ruminants in many countries in the temperate climates and often causes important production losses in infected animals [1, 9, 11, 14, 29, 39]. Natural fasciolosis in sheep develops clinical manifestations of acute, subacute and chronic infection according to numbers of metacercaria ingested in a period of time [1, 4, 11, ...
BACKGROUND Peroxisome proliferator-activated receptor (PPAR) agonists reduce voluntary ethanol (EtOH) consumption in rat models and are promising therapeutics in the treatment for drug addictions. We studied the effects of different classes of PPAR agonists on chronic EtOH intake and preference in mice with a genetic predisposition for high alcohol consumption and then examined human genomewide...
BACKGROUND In rodents and pigs, it has shown that carnitine synthesis and uptake of carnitine into cells are regulated by peroxisome proliferator-activated receptor α (PPARA), a transcription factor which is physiologically activated during fasting or energy deprivation. Dairy cows are typically in a negative energy balance during early lactation. We investigated the hypothesis that genes of ca...
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