نتایج جستجو برای: post transcriptional gene regulation

تعداد نتایج: 1884247  

2012
Daniel Beisang Paul R. Bohjanen

In order to assure the precise utilization of genetic information, gene expression is regulated at the level of transcription as well as multiple post-transcriptional levels including splicing, transport, localization, mRNA stability, and translation [1],[2],[3],[4],[5],[6],[7]. During evolution, cells developed precise mechanisms to ensure that each transcript is appropriately stored, modified...

Journal: :acta medica iranica 0
maryam moazeni division of molecular biology, department of medical mycology & parasitology, school of public health, tehran university of medical sciences, tehran, iran. mohammad reza khoramizadeh department of medical biotechnology, school of advanced technologies in medicine, tehran university of medical sciences, tehran, iran. ladan teimoori-toolabi department of molecular medicine, biotechnology research center, pasteur institute of iran, tehran, iran. fatemeh noorbakhsh department of biology, islamic azad university, varamin-pishva branch, varamin, iran. sassan rezaie division of molecular biology, department of medical mycology & parasitology, school of public health, tehran university of medical sciences, tehran, iran. and department of medical biotechnology, school of advanced technologies in medicine, tehran university of medical sciences, tehran, iran.

efg1 transcription factor is believed to be the main regulator of hyphal formation under many different conditions. in addition, it is responsible for positive regulation of the expression of several hyphal-specific genes. sap5, which encodes secreted aspartic proteinase, is one of the mentioned genes and is crucial for pathogenicity properties. in the present work we have established the exper...

2012
Garrett M. Dahm Matthew M. Gubin Joseph D. Magee Patsharaporn Techasintana Robert Calaluce Ulus Atasoy

As a result of the development of high-throughput sequencing and efficient microarray analysis, global gene expression analysis has become an easy and readily available form of data collection. In many research and disease models however, steady state levels of target gene mRNA does not always directly correlate with steady state protein levels. Post-transcriptional gene regulation is a likely ...

Journal: : 2023

Population aging is accelerating worldwide, straining the global economy and health services. Cellular senescence a significant contributor to various age-related neurological neuropsychiatric disorders, including Alzheimer’s disease Parkinson’s disease. Some external factors, such as exposure ionizing radiation, can accelerate aging. In recent years, it has become known that post-transcription...

Journal: :The EMBO journal 2009
Joris Pothof Nicole S Verkaik Wilfred van IJcken Erik A C Wiemer Van T B Ta Gijsbertus T J van der Horst Nicolaas G J Jaspers Dik C van Gent Jan H J Hoeijmakers Stephan P Persengiev

DNA damage provokes DNA repair, cell-cycle regulation and apoptosis. This DNA-damage response encompasses gene-expression regulation at the transcriptional and post-translational levels. We show that cellular responses to UV-induced DNA damage are also regulated at the post-transcriptional level by microRNAs. Survival and checkpoint response after UV damage was severely reduced on microRNA-medi...

2016
Jing Li Yanzhi Wang Yongxia Zhang Weiyao Wang Vivian F Irish Tengbo Huang

Plant organ growth requires the proper transition from cell proliferation to cell expansion and differentiation. The CIN-TCP transcription factor gene TCP4 and its post-transcriptional regulator microRNA319 play a pivotal role in this process. In this study, we identified a pathway in which the product of the C2H2 zinc finger gene RABBIT EARS (RBE) regulates the transcription of TCP4 during Ara...

Journal: :Journal of Biological Chemistry 2002

2014
Guy R. Pilkington Katarzyna J. Purzycka Jenifer Bear Stuart F. J. Le Grice Barbara K. Felber

Post-transcriptional regulatory mechanisms of several complex and simple retroviruses and retroelements have been elucidated, with the exception of the gammaretrovirus family. We found that, similar to the other retroviruses, gag gene expression of MuLV and XMRV depends on post-transcriptional regulation mediated via an RNA sequence overlapping the pro-pol open reading frame, termed the Post-Tr...

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