Central nervous system (CNS) metastases can occur with any primary systemic cancer, but some primary cancers such as melanoma have a specific predilection for the CNS. Brain metastasis is the most common CNS metastasis, occurring in 15% of all cancer patients (Posner, 1995). Leptomeningeal metastasis is less common, 3% to 8%, and epidural metastasis occurs in approximately 5% of cases (Posner, ...