A polarized cell, to maintain distinct basolateral and apical membrane domains, must tightly regulate vesicular traffic terminating at either membrane domain. In this study we have examined the extent to which microtubules regulate such traffic in polarized cells. Using the polymeric immunoglobulin receptor expressed in polarized MDCK cells, we have examined the effects of nocodazole, a microtu...

Ambient S annealing was adopted to regulate the crystallinity of a ZnS microsphere, which resulted in a significant improvement in the photocatalytic hydrogen production activity (PHPA). Moreover, with S ambient treatment, wurtzite ZnS showed better PHPA than sphalerite ZnS, possibly because the inter-polar electric field of the wurtzite phase could promote the separation of photo-excited elect...

Vertebrate internal exons are usually between 50 and 400 nt long; exons outside this size range may require additional exonic and/or intronic sequences to be spliced into the mature mRNA. The mouse polymeric immunoglobulin receptor gene has a 654 nt exon that is efficiently spliced into the mRNA. We have examined this exon to identify features that contribute to its efficient splicing despite i...

In the title polymeric complex, [Fe{OS(CH3)2}2{Ag(CN)2}2], the FeII cation is located at an inversion centre and is coordinated by four cyanide (CN-) anions and two dimethyl sulfoxide mol-ecules in a slightly compressed N4O2 octa-hedral geometry, the AgI cation is C-coordinated by two CN- anions in a nearly linear geometry. The CN- anions bridge the FeII and AgI cations to form a two-dimensiona...

Rat hepatocytes in short-term monolayer cultures bound radiolabeled polymeric rat IgA but not IgG. The binding of 125I-IgA was inhibited equally well by unlabeled polymeric IgA and by antiserum to rat secretory component (SC). The antibody to SC, after specific purification and radiolabeling, was bound to hepatocytes as effectively as the IgA. These results indicate that SC acts as the receptor...

A detailed experimental study of sound propagation in liquids contained by pipes constructed of polymeric materials is discussed. Experiments were conducted with vertically aligned cylinders containing water ensonified at one end by a piston-driven sound source. Significant sound attenuation (as much as 60 dB} was observed in pipes made of flexible polymeric materials, the effect increasing wit...

The past few years have seen many advances in our understanding of the dynamics of polymeric fluids. These include improvements on the successful reptation theory; an emerging molecular theory of semiflexible chain dynamics; and an understanding of how to calculate and classify “phase diagrams” for flow-induced transitions. Experimentalists have begun mapping out the phase behavior of wormlike ...

immunofixation (2), and beta-mercaptoethanol reduction (3) of serum, with subsequent zone electrophoresis (Figure 1). In each instance, such reduction caused the band to disappear. The immunofixation and immunoelectrophresis procedures confirmed the presence of polymeric, polyclonal 1gM. One would expect that a discrete band would still be present on zone electrophoresis after reduction if 1gM ...

Polymeric nanoparticle systems (nanocapsules and nanospheres) present potential applications as drug delivery systems. Nevertheless, their full applications have not been exploited due to their limited shelf life when stored in aqueous medium. Drying polymeric nanoparticles using spray-drying represents a promising platform to improve the physicochemical stability of formulations and/or to cont...

nimodipine (nm), as a lipophilic calcium channel blocker indicated for the prevention and treatment of neurological disorders, suffers from an extensive first pass metabolism, resulting in low oral bioavailability. polymeric micelles, self-assembled from amphiphilic polymers, have a core-shell structure which makes them unique nano-carriers with excellent performance as drug delivery. this inve...