n Evidence summary Polycystic ovarian syndrome is a condition of unexplained hyperandrogenic chronic anovulation that affects at least 4% of women of reproductive age. Because PCOS is a clinical syndrome, no single diagnostic criterion is sufficient for diagnosis. Clinical features include menstrual irregularities or infertility, hirsutism, male-pattern balding, acne, ovarian enlargement, and s...

Background Evaluation of anti-mullerian hormone (AMH) cut-off levels in assisted reproductive technology (ART) as predictive factor for individualization of stimulation protocols and to avoid ovarian hyperstimulation syndrome (OHSS). MaterialsAndMethods In a retrospective study, 177 infertile patients were assessed for AMH in serum and follicular fluid (FF) on the day of follicular puncture (FP...

The clinical use of anti-Müllerian hormone (AMH) has increased exponentially due to its unique relationship with the ovarian reserve and ability to predict ovarian response, facilitate pretreatment counselling and individualize treatment strategies to minimize the risk of ovarian hyperstimulation syndrome. There is now a rapidly increasing literature examining additional possibilities for AMH, ...

BACKGROUND Premature adrenarche refers to the early maturation of the adrenal zona reticularis such that the resultant modest hyperandrogenism causes the early appearance of pubic hair before the age of 8 years in girls and 9 years in boys. The precise etiology of premature adrenarche is not known. However, recent studies indicate that certain girls with premature adrenarche are at risk of deve...

Polycystic ovarian syndrome (PCOS), also known as SteinLeventhal syndrome, is a common gynecological disorder characterized by hypergonadotrophism, hirsutism, obesity, oligomenorrhea and commonly associated with infertility. PCOS is a complex clinical picture and presents a multifaceted etiology related to imbalance of the hypothalamic-pituitary-adrenal (HPA) axis, thyroid involvement and metab...

In adults, the ovary is characterized with extensive angiogenesis and regular intervals of rapid growth. Ovarian function is dependent on the network of angiogenic vessels which enable the follicle and/or corpus luteum to receive oxygen, nutrients and hormonal support. Abnormal angiogenesis is involved in the induction and development of pathological ovary, such as polycystic ovary syndrome and...

Polycystic ovarian syndrome (PCOS) is the most common female endocrine disorder, affecting approximately 5%-10% of all females and 4-6% of adolescent girls and young women. PCOS is a hormonal disorder that involves multiple organ systems within the body and is believed to be fundamentally caused by insensitivity to insulin.1 It can be diagnosed in all phases of life in girls as young as 8-9 yea...

Background: Polycystic ovarian syndrome is one of the most commen hyper androgenic disorders affecting women, its prevalence being estimated at 5% – 10%. Our goal was to survey abnormal glucose tolerance, insulin resistance and incidence of diabetes type 2 in patients with polycystic ovary syndrome. Materials and methods: This investigation is a descriptive – analytic study which is done to su...