A 61-year-old man had hypertension with stenosis in the left renal artery. When his fever, abdominal pain, and renal dysfunction progressed, he was admitted to our hospital. He was diagnosed with polyarthritis nodosa. His renal function rapidly deteriorated despite immunosuppressive therapy. His digestive tract perforated twice, and he subsequently died. An autopsy revealed that aortic intimal ...

Intracerebral haemorrhage is a rare complication of polyarteritis nodosa (PAN). We present the clinico-pathologic findings of a 62 year-old patient with systemic involvement by PAN, who developed temporary decrease of consciousness and a mild left hemisyndrome due to a small right dorsal thalamic haemorrhage. No clear cause for the haemorrhage was found on postmortem examination.

Hypertrophic osteo-arthropathy is most commonly associated with bronchopulmonary or pleural diseases. It has also been described in several apparently unrelated conditions and occasionally in patients with no other recognizable disease. The literature is reviewed by Mendlowitz (1942). This paper reports hypertrophic osteo-arthropathy in a patient with polyarteritis nodosa and describes the effe...

The occurrence of renal vein thrombosis in a case each of polyarteritis nodosa and the Henoch-Schoenlein syndrome is reported. It is suggested that obliteration of the arterioles that supply the walls of the veins may have initiated the venous thrombosis in these two cases.

Allergic granulomatosis and angiitis is a disorder characterized by extravascular granulomas, hypereosinophilia, and pulmonary and systemic small-vessel vasculitis. The combination of allergic granulomatosis and angiitis is associated with asthma, typically of adult onset, and allergic rhinitis.1 Churg and Strauss first described this disorder in 1951, when they reviewed 13 autopsy cases that w...

A six-year old boy presented with dry gangrene of toes and fingers with hypertension with no other systemic abnormalities. He had persistently high inflammatory parameters, was diagnosed as childhood classic polyarteritis nodosa and showed improvement with immunosuppressants along with antihypertensives. Toe gangrene required amputation in view of superadded infection.

We previously reported a case in which steroid-induced psychosis was eliminated with risperidone treatment in a patient with polyarteritis nodosa (PN). In the present report, we longitudinally tracked the serum levels of brain-derived neurotrophic factor (BDNF). We found that corticosteroid lowered serum BDNF levels, and improvement of psychiatric symptoms was intact with the serum BDNF levels ...

OBJECTIVES To determine the incidence and clinical features of paediatric primary vasculitis in patients from one centre in Eastern China. METHODS Medical records of paediatric patients diagnosed with primary vasculitis between January 1999 and December 2013 were retrospectively reviewed. For Henoch-Schönlein purpura (HSP) and Kawasaki disease (KD), patients included in the analyses had data ...