Enzyme linked immunosorbent assay (ELISA) for ß 2 -Glycoprotein I dependent anticardiolipin antibodies (ß 2 I aCL) was carried out in 82 women experiencing 3 or more recurrent pregnancy losses and 82 normal healthy controls. The mean aCL levels were 14.53 (μ/ml) ± 16.22 in women with repeated abortions and 7.26 (μ/ml) ± 3.65 in controls. The difference in the values between the two groups was f...

Background Both short and long sleep duration were previously associated with incident dementia, but underlying mechanisms of this association remains unknown. This project aims to evaluate how self-reported its change over time associate (A)myloid, (T)au, (N)eurodegeneration (V)ascular neuroimaging markers Alzheimer’s disease (AD). Method Within the Framingham Heart Study, two samples studied:...

Transforming growth factor-ß (TGF-ß) signaling is implicated in the pathogenesis of fibrosis in scleroderma or systemic sclerosis (SSc), but the precise mechanisms are poorly understood. The immediate-early gene Egr-1 is an inducible transcription factor with key roles in mediating fibrotic TGF-ß responses. To elucidate Egr-1 function in SSc-associated fibrosis, we examined change in gene expre...

Bone morphogenetic protein (BMP)-2 induces bone and cartilage tissue formation. Large amounts of BMP-2 are difficult to purify or to produce in vitro using eukaryotic cells. The goal of the present study was to assess the clinical use of Escherichia coli-derived recombinant human BMP-2 (ErhBMP-2) on bone fusion after cervical and lumbar spine surgery in a goat model, compared with the standard ...

The uterine cervix is a rare implantation site for ectopic pregnancy, surgical management should be carefully considered due to the risk of severe hemorrhage associated with this treatment. Methotrexate (MTX) is well documented as an effective medical approach in early gestations and low human chorionic gonadotropin (ß-hCG) levels yielding good results. This is the case,of a 39 year old woman w...

Although recreational dancing is associated with increased physical and psychological well-being, little is known about the harmful effects of excessive dancing. The aim of the present study was to explore the psychopathological factors associated with dance addiction. The sample comprised 447 salsa and ballroom dancers (68% female, mean age: 32.8 years) who danced recreationally at least once ...

The derivatives of hydroxybenzoic and hy­ droxycinnamic acids are widespread in the plant kingdom. A considerable number of these deriva­ tives are well known [1], Nevertheless there is only little existing information about the glucosides of these compounds and their distribution. Syringic acid-O-ß-D-glucoside was detected in Anodendron affine. [2], as well as /»-hydroxybenzoic acid-O-ß-D-gluc...

Two new triterpenoid saponins have been isolated from leaves and flowers of Crotalaria madurensis Wight&Arn named; sophradiol 3-O-β-D-C1-glucopyranosyl-(1''→4')-O-β-DC1 glucuronopyranoside (3) and sophradiol 3-Oα-LC4rhamnopyranosyl (1'''→4'')-O-ß-D-C1 glucopranosyl-(1''→6')-O-ß-DC1-glucopyranoside (4) beside myo-inositol (1) and three other triterpene saponin their structures were established a...