نتایج جستجو برای: plumbagin
تعداد نتایج: 378 فیلتر نتایج به سال:
Inhibition of Aldose Reductase (AR) is very important in terms preventing many diabetic complications such as retinopathy, neuropathy, and cataract. In this study, inhibition effects some antiproliferative agents, which have been shown to biological activities besides their anticancer properties, on the AR enzyme, a diabetes-related were investigated. Biochanin A compound with an IC50 value 4.4...
Abstract Background Obesity‐related asthma, a specific type of tends to have more severe symptoms and frequent exacerbations, it is insensitive standard medications. Plumbagin (PLB) has many positive effects on human health. However, remains unclear whether PLB protects against obesity‐related asthma. The study investigated the effect Methods Four‐week‐old male C57BL6/J mice were fed either sta...
Barleria alluaudii and Diospyros maritima were both investigated as part of an ongoing search for synergistic TRAIL (tumor necrosis factor-α-related apoptosis-inducing ligand) sensitizers. As a result of this study, two naphthoquinone epoxides, 2,3-epoxy-2,3-dihydrolapachol (1) and 2,3-epoxy-2,3-dihydro-8-hydroxylapachol (2), both not previously isolated from natural sources, and the known 2-me...
A Bacillus subtilis sigM null mutant, lacking the extracytoplasmic function sigma(M) protein, was sensitive to paraquat (PQ), a superoxide-generating reagent, but not to the redox stress-inducing compounds hydrogen peroxide, cumene hydroperoxide, t-butyl hydroperoxide, or diamide. Surprisingly, a sigM mutant was only sensitive to superoxide-generating compounds with a dipyridyl ring such as PQ,...
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