Spirometry, body plethysmography, maximal expiratory flow-volume curves (MEFV-curves) with air and with heliox (80% He + 20% O2) before and after inhalation of bronchodilators were studied in a group of 20 adult cystic fibrosis (CF) patients. Most of them showed prominent bronchial obstruction and seven also had evidence of restrictive pulmonary disease. Large differences were observed between ...

The assumption that the respiratory system behaves with 2 df of motion in healthy persons allows calibration of respiratory inductive plethysmography (RIP) with spirometry (SP). To ascertain whether RIP could be calibrated by the same assumption in patients with lung disease, even though at least 3 df of motion are visualized (ie, upper and lower rib cage and upper and lower abdomen move out of...

Pathophysiological considerations predict that exercise blood flows at comparable work loads must always be reduced in claudicants in comparison to normal subjects. The present study verified that the exercise blood flow determined by 133xenon clearance measurements in the gastrocnemius muscle in claudicants and in a control group differed widely. As expected, a statistically significant correl...

The authors explored the relative utility of pulmonary function tests (PFTs) and computed tomography (CT) to characterize the progression of papain induced emphysema in sheep (n = 12). PFT included plethysmography (FRC(pleth)), helium dilution (FRC(He)), and expired reserve volume (ERV). Following papain, FRC(pleth) and FRC(He) were unchanged; ERV decreased hence residual volume increased signi...

OBJECTIVE While chronic cerebrospinal venous insufficiency (CCSVI) can be characterized using cervical plethysmography, much remains unknown about the haemodynamics associated with this procedure. The aim of the study was therefore to gain a deeper understanding of the observed haemodynamics. METHOD Forty healthy controls and 44 CCSVI patients underwent cervical plethysmography, which involve...

Impedance plethysmography has great potential in the non-invasive detection of dangerous iliofemoral thrombosis. It was used to examine 198 patients undergoing total hip replacement for evidence of proximal venous segment thrombosis. There were 13 abnormal results, and subsequent venography in 12 of these revealed a false-positive rate of 4.0%; there was one false-negative result giving a sensi...

The widespread use of genetically altered mouse models of experimental asthma has stimulated the development of lung function techniques in vivo to characterize the functional results of genetic manipulations. Here, we describe various classical and recent methods of measuring airway responsiveness in vivo including both invasive methodologies in anesthetized, intubated mice (repetitive/non-rep...