background: hepatitis c virus (hcv) infection is the most common transfusion transmitted disease in poly-transfused patients worldwide. in this study we aimed to evaluate the effects of pegylated interferon alfa-2a (peg-ifn a-2a) in reducing serum alt and eradicating serum hepatitis c virus (hcv) rna in hcv infected polytransfused thalassemic patients. materials and methods: a cohort of 51 hcv-...

The aim of the current study was to determine the extent to which pleasant and unpleasant emotional states impact the initiation of forward gait. Participants initiated gait and walked for several steps following the presentation of low arousing pleasant, high arousing pleasant, low arousing unpleasant, high arousing unpleasant, and neutral pictures. Reaction time, displacement, and velocity of...

Affective startle modulation in the electromyographic (EMG), auditory startle evoked potentials, and visually evoked potentials (VEPs) were assessed while subjects evaluated pleasant, unpleasant, and neutral adjectives. Acoustic startle probes were presented at random time points 2.5-4.0 s after word onset. The visual P2 and P3 potentials were generally larger during processing of emotional tha...

Does hedonic appreciation evolve differently for pleasant odors and unpleasant odors during normal aging? To answer this question we combined psychophysics and electro-encephalographic recordings in young and old adults. A first study showed that pleasant odorants (but not unpleasant ones) were rated as less pleasant by old adults. A second study validated this decrease in hedonic appreciation ...

Previous research suggests that more involvement in various activities can help delay cognitive decline in older adults. Few studies have examined both the impact of frequency and perceived enjoyment of different types of activities on cognition. This study analyzed the relationship between frequency and pleasure of activities and cognition by running correlations using the five different subsc...

People base many decisions on affective forecasts, predictions about their emotional reactions to future events. They often display an impact bias, overestimating the intensity and duration of their emotional reactions to such events. One cause of the impact bias is focalism, the tendency to underestimate the extent to which other events will influence our thoughts and feelings. Another is peop...

Cultural events are relevant attractions in contemporary cities that can be understood as celebrations, but also agents of urban change. The primary objective this study is to identify emerging themes the area cultural events, especially Night Museums, and highlight relationships among museums places learning aesthetic satisfaction. To reach goal, an exploratory descriptive was conducted. Multi...

PURPOSE To assess the efficacy and tolerability of sunitinib dosing schedule of 2 weeks on and 1 week off (schedule 2/1) vs. the traditional schedule of 4 weeks on and 2 week off (schedule 4/2) and its influence on health-related quality of life (HRQoL) in Chinese patients with metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS A retrospective analysis of 108 patients with mRCC who...

There is much evidence for the adaptive value of positive affect. Empirical work examining different facets of positive affect and their consequences for psychological adaptation remains sparse, however. This study (young, middle-aged, and older adults; N = 293) investigated the links between two dimensions of positive affect (positive involvement and pleasant affect) and two lifestyles (hedoni...