نتایج جستجو برای: platelet index
تعداد نتایج: 502894 فیلتر نتایج به سال:
Background. Sepsis and septic shock are the most severe clinical expressions of infection, despite having characterized several decades ago, remain as a diagnostic challenging this can delay treatment increasing hospital cost secondary to pathology.
 Our objective was determine usefulness mean platelet volume delta (ΔVPM) predictor mortality.
 Methodology. We performed an observationa...
Although thromboxane A2 is a potent platelet agonist and vasoconstrictor in vitro, our knowledge of its pathophysiologic importance in human disease is limited. To facilitate the elucidation of its role in vivo, we sought to define a human syndrome in which pharmacologic interventions designed to inhibit the biosynthesis or biologic actions of thromboxane A2 might be appropriately assessed. Pat...
Objective.—The present study was undertaken to investigate the alterations in platelet 5-HT 2 receptor binding in patients with tension-type headache. Background.—Serotonin (5-HT) has an important but complex role in pain modulation. The involvement of serotonin in tension-type headache has been investigated by studying serotonin in peripheral blood, but results have been inconclusive. There ar...
BACKGROUND Beyond their role in hemostasis and thrombosis, platelets are important for modulating inflammatory reactions. Activated platelets play a role in the pathomechanism of inflammatory diseases such as asthma, but little is known about platelet activation in chronic skin inflammation, including atopic dermatitis (AD) and psoriasis. Furthermore, the relationship between platelet activatio...
We created a predictive model using serum-based biomarkers for advanced fibrosis (F3 or more) in patients with chronic hepatitis B (CHB) and to confirm the accuracy in an independent cohort.A total of 249 CHB patients were analyzed. To achieve our study aim, a training group (n = 125) and a validation group (n = 124) were formed. In the training group, parameters related to the presence of adva...
Liver fibrosis is critical for liver-related outcomes and mortality in chronic liver disease, irrespective of etiology, including nonalcoholic fatty disease (NAFLD). NAFLD has been viewed as an independent correlate cardiovascular risk. This review article briefly describes the cellular molecular pathomechanisms underlying hepatic fibrosis. We then address noninvasive assessment Finally, we dis...
OBJECTIVES We aimed to investigate whether clopidogrel-induced inhibition of platelet reactivity could reduce the level of circulating endothelial cells (CEC), reflecting the endothelial injury induced by percutaneous coronary intervention (PCI). BACKGROUND Clopidogrel loading dose before percutaneous coronary angioplasty (PCI) reduces platelet activation through a selective and irreversible ...
Giriş ve Amaç: Akut inmeye bağlı mortalite morbidite oranları yüksek olduğundan bu hastaların erken prognoz öngörüsünü yapmak önemlidir. Acil serviste iskemik ya da hemorajik inme tanısı alan Ortalama trombosit hacmi (MPV), Platelet (PLT) MPV/PLT değerleri ile demografik özellikleri, triaj kodu, sonlanımı, vital parametreleri Glaskow Koma Skalası (GKS) arasındaki ilişki değerlendirilmeye çalışı...
Abstract Background and Objectives Immune platelet refractoriness is a complication of blood transfusion in patients with multiple platelet transfusions. Antibodies against surface antigens, including human platelet antigens (HPAs) and human leukocyte antigens (HLAs), can be produced which can cause the degradation of transfused platelets by macrophages. In this study, the frequency of platele...
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