The mechanism of D-penicillamine induced thrombocytopenia in rheumatoid arthritis was investigated by measuring platelet life-span and platelet production rate in 2 groups of rheumatoid arthritis patients treated with 250-750 mg/day D-penicillamine, 14 with a normal platelet count and 9 with thrombocytopenia (platelet count 50-130 X 10(9)/1). Age matched control patients not treated with D-peni...

Methods: 112 patients and 42 controls were included in this study. Group 1 consisted of males only, Group 2 consisted of females only and Group 3 consisted of both sexes. In all groups, WBC (white blood cell count), RBC (red blood cell count), rdw (red cell distribution width), platelet count, MPV, pdw (platelet distribution width) and NLR parameters from CBC (complete blood count) were compare...

In view of the high incidence of thromboembolic complications after the insertion of cardiac valve prostheses, platelet adhesiveness and aggregation was measured in whole blood before, during, and for several days after this operation in 10 patients. Cardiopulmonary bypass resulted in a profound decrease in the platelet count, in the number of adhesive platelets, and in platelet aggregation. Th...

INTRODUCTION Thrombocytosis accompanying solid tumors and predicting the prognosis of malignant tumors has been the subject of intensive research lately. Reports so far have evaluated the role of preoperative platelet count. In our present study we looked at the effect of tumor removal on platelet count and the predictive power of postoperative thrombocytosis on the survival of patients with co...

We compared whole blood platelet aggregation, adenosine triphosphate release, platelet count, platelet crit (percentage volume of platelets), and mean platelet volume during the acute, subacute, and chronic periods of cerebral thrombosis in 22 patients with value in 29 controls. During the acute and subacute periods, platelet aggregation, platelet count, platelet crit, and mean platelet volume ...

blood transfusion centers are under considerable pressure to produce platelet concentrates with a shelf life limit of 3 to 5 days. many approaches have been investigated experimentally to produce new hemostatically active platelet products that are capable of long term storage. in this article infusible platelet membrane will be explained as a platelet substitute versus conventional liquid-stor...

abstract background immune thrombocytopenic purpura (itp) is a common autoimmune bleeding condition in children that is characterized by a decrease in the platelet count. the aims of this study were to define epidemiologic features of patients with primary itp who were admitted to mofid children's hospital, tehran, iran, in a 5-year period. methods we retrospectively studied the records of pati...

We recently encountered a patient with thrombocytopenia secondary to multiple drug therapy, disseminated prostatic adenocarcinoma, and sepsis who had a sudden decrease in his platelet count as enumerated by the Cell-DYN 4000 hematology analyzer (Abbott Diagnostics, Santa Clara, CA). A manual platelet count performed thereafter was even lower. The etiology of the spurious platelet count was clar...

Background: The platelet volume parameters have been widely available as part of full blood count profile on automated haematology analyzers. However, the mean platelet volume (MPV) and other platelet indices are used less often and are poorly understood. Platelet volume data is generated at no extra cost as part of full blood count profile. Low platelet counts can have myriad cause which can b...