A sensitive and simple Gas Chromatographic-Mass Spectrometric method was developed and validated for the determination of captopril in human plasma. Thiosalicylic acid was used as an internal standard, and plasma extraction was performed by solid phase extraction. The limit of quantification was 0.5 ng/mL with signal to noise ratio greater than 5. The calibration curve was linear from 1 to 160 ...

An account is presented of the work done in the USSR on the generation of thermal plasma, plasma melting, and plasma jet processes. The various methods of plasma generation are reviewed, such as arc plasma generators and high frequency (HF) plasma generators including HF-induction plasmatrons, HF-capacity plasmatrons and HF-flame plasmatrons. Plasma melting techniques covered include plasma-arc...

We determined the through blood and plasma concentrations of tacrolimus from the day of transplantation through 30 days posttransplantation in four liver and four kidney transplant patients by three different methods. The first method involved a solid phase extraction of the blood or plasma using Sep-Pak columns (SPs) followed by quantitation of tacrolimus using an enzyme-linked immunosorbent a...

Hepatic blood flow, hepatic extraction of renin, and hepatic clearance of renin were compared in normal conscious dogs, in dogs with constriction of the thoracic inferior vena cava (as a model of low-output heart failure), and in dogs with an aortic-caval fistula (high-output heart failure). Both "failure" preparations showed marked sodium retention. Renin was measured by methods described prev...

Accurate and rapid diagnosis of CMV disease in immunocompromised individuals remains a challenge. Quantitative polymerase chain reaction (QPCR) methods for detection of CMV in peripheral blood mononuclear cells (PBMC) have improved the positive and negative predictive value of PCR for diagnosis of CMV disease. However, detection of CMV in plasma has demonstrated a lower negative predictive valu...

Transforming CO2 into value-added chemicals is crucial to realizing a carbon–neutral economy, and plasma-based conversion, Power-2-X technology, offers promising route an efficient scalable process. This paper investigates the effects of post-plasma placement converging–diverging nozzle in vortex-stabilized 2.45 GHz microwave plasma reactor increase energy efficiency conversion. The CDN leads 2...

BACKGROUND Several markers are available to estimate the glomerular filtration rate (GFR) in patients. Cystatin C is a relatively new marker and has been suggested as an alternative for creatinine. Numerous studies have been performed to evaluate the usefulness of cystatin C to estimate GFR. The aim of this study is to compare the renal extraction of cystatin C with that of 125I-iothalamate in ...