tobacco smoke contains numerous compounds, many ‎of which are oxidants and capable of producing free radical and enhancing ‎the oxidative stress. the aim of this study was to investigate the effect of cigarette smoking on the erythrocyte antioxidative enzyme activities and the plasma ‎concentration of their cofactors. ‎sixty eight healthy men were enrolled, 32 of whom had never smoked and 36 ha...

Plasma concentrations of some micronutrients are altered in the setting of acute infectious or inflammatory stress. Previous studies have provided conflicting evidence concerning the extent and direction of changes in plasma zinc concentrations during the acute phase response. We carried out an observational cohort study in 689 children enrolled in a randomized trial of zinc supplementation dur...

BACKGROUND Leukoplakia is a common, potentially premalignant lesion with malignant transformation rate from 1 to 17% with highest transformation rate for the lesions on the floor of the mouth, soft palate and tongue. One of the main etiological factors is consuming areca nut and its commercial preparations which generate high levels of reactive oxygen species during their metabolism. So the aim...

background : the role of minerals on parasite persistency and the interaction between minerals and animal responses to the parasite infestation is not clear. for these reasons, the present re­search was aimed to compare copper, zinc and iron status in sheep with parasitic myocarditis and healthy ones in 2009. methods : blood and heart tissue samples were collected from 145 slaughtered sheep and...

BACKGROUND Patients undergoing hemodialysis (HD) have low plasma levels of zinc (Zn), high plasma levels of copper (Cu), and exhibit increased oxidative stress, inflammation, and immune abnormalities. We evaluated the effects of Zn supplementation on abnormal plasma Cu/Zn ratios and clinical outcomes in HD patients. DESIGN AND METHODS Patients on long-term HD with lower than normal plasma con...

The relative proportions of metal residing in ore in the lithosphere, in use in products providing services, and in waste deposits measure our progress from exclusive use of virgin ore toward full dependence on sustained use of recycled metal. In the U.S. at present, the copper contents of these three repositories are roughly equivalent, but metal in service continues to increase. Providing tod...

background: copper and zinc are the elements with numerous physiological activities.  copper  (cu)  has  an  important  role  in  angiogenesis  and  acts  by increasing vascular endothelial growth factor (vegf). serum levels of copper will be increased in cancer incidence, progression and recurrence. the aim of this study was to measure blood levels of copper, zinc, and the ratio of cu /zn, as ...