Studies of isolated craniosynostosis have shown biomechanical and biochemical influences on the craniofacial phenotype, resulting from both genetic and epigenetic factors. Much less attention has been directed toward the morphology of the brain, despite the interactive nature of the developing skull and developing brain. The aim of this study is to define the morphology of the brain in nonsyndr...

Dot lattices are very simple multi-stable images where the dots can be perceived as being grouped in different ways. The probabilities of grouping along different orientations as dependent on inter-dot distances along these orientations can be predicted by a simple quantitative model. L. Bleumers, P. De Graef, K. Verfaillie, and J. Wagemans (2008) found that for peripheral presentation, this mo...

We present a new method to analyze, classify and characterize 3D landmark-based shapes. It is based on a framework provided by oriented matroid theory, that is on a combinatorial encoding of convexity properties. We apply this method to a set of skull shapes presenting various types of coronal craniosynostosis.

This investigation determined relationships between coronal vertical alignment (CVA) and sagittal vertical alignment (SVA) variables calculated from radiographs and surface markers representing bony landmarks. Biplanar radiographs were taken on 28 subjects (standing) after 2 metallic surface markers were placed on the skin superficial to C7 and S2. The CVA-R and SVA-R were measured on the radio...

OBJECTIVE To evaluate and summarize the evidence comparing nonsurgical therapies in the treatment of infants with deformational plagiocephaly. DATA SOURCES Scientific articles and abstracts published in English between January 1978 and August 2007 were searched from 5 online literature databases, along with a manual search of conference proceedings. STUDY SELECTION Studies were selected and...

Slow, large deformations of human brain tissue—accompanying cranial vault deformation induced by positional plagiocephaly, occurring during hydrocephalus, and in the convolutional development—has surprisingly received scarce mechanical investigation. Since the effects of these deformations may be important, we performed a systematic series of in vitro experiments on human brain tissue, revealin...

Correspondence: Joseph H. Shin, MD Associate Professor of Surgery Director, Yale Craniofacial Center Section of Plastic Surgery, Department of Surgery Yale University School of Medicine. P.O. Box 208041 New Haven, Connecticut 06520-8041 1.MD, Associate Professor of Surgery Section of Plastic Surgery, Department of Surgery, Yale University School of Medicine. 2.MD,PhD, Professor Adjunto da Disci...

BACKGROUND The authors investigated the effectiveness of conservative (repositioning therapy with or without physical therapy) and helmet therapy, and identified factors associated with treatment failure. METHODS A total of 4378 patients evaluated for deformational plagiocephaly and/or deformational brachycephaly were assigned to conservative (repositioning therapy, n = 383; repositioning the...