BACKGROUND Advancing age is linked to a decrease in beneficial bacteria such as Bifidobacterium spp. and reduced aspects of innate immune function. OBJECTIVES We investigated whether daily consumption of a probiotic [Bacillus coagulans GBI-30, 6086 (BC30); GanedenBC(30)] could improve immune function and gut function in men and women aged 65-80 y, using a double-blind, placebo-controlled cros...

Background and objectives: Oligo-amenorrhea is one of the most common symptoms in poly cystic ovarian syndrome (PCOS) patients and Nigella sativa is a medicinal plant used in Iranian traditional medicine for the treatment of oligo-amenorrhea. The aim of this study was to evaluate the effect of N. sativa oil on oligo-amenorrhea in patients with PCOS. Me...

hot flash is among the most common complaints of menopausal women, affecting their career, social activities and quality of life. this study aimed to investigate the effects of valerian on hot flashes in menopausal women. in this double blind clinical trial, 68 menopausal women with the chief complaint of hot flash were enrolled using sampling at hand and were randomly divided into drug and pla...

background and aims: although laparoscopy itself is a new step to improve the quality of different types of surgery, reducing their complications postoperative pain remains a major problem. this study compares the effects of low dose oral gabapentin with placebo to control postoperative pain in patients undergoing laparoscopic cholecystectomy . materials and methods: in this double-blind random...

Scientific studies support recommendations to increase dietary soluble fiber as part of hyperlipidemia treatment. Rice bran contains minimal soluble fiber, but rice bran oil has a hypolipidemic effect. Full-fat rice bran was compared with oat bran and a rice starch placebo in hyperlipidemic humans to see if it might have a role in the treatment of hyperlipidemia. Moderately hypercholesterolemic...

In a double blind placebo controlled trial, 434 patients with suspected myocardial infarction were randomised to treatment with nifedipine (n = 217) or placebo (n = 217) within six hours from the onset of chest pain. During the treatment period of 48 hours, a 10 mg capsule containing nifedipine or placebo was given sublingually every four hours for 24 hours, then orally every four hours for the...

The type and the amount of binders decisively influence the characteristics of tablets prepared by wet granulation procedure. Commonly used binders like acacia, gelatin, starch and hydrolyzed starch have natural origin. The aim of this study was to evaluate the effectiveness of a new binder extracted from Hibiscus esculentus (Okra gum) in tableting. binder Hibiscus esculentus gum was extracted ...

BACKGROUND Ankylosing spondylitis (AS) is a chronic inflammatory autoimmune disease. Kunxian capsule, a Chinese patent medicine which has been used in the treatment of immunologic diseases for many years in China, has anti-inflammatory and immunoregulatory effects. This study investigates the efficacy and safety of Kunxian capsules in the treatment of AS. METHOD This was a randomized, double-...