In a double-blind, crossover, randomized and placebo-controlled trial; 28 men and women ingested a placebo (PLA), 3 g of creatine nitrate (CNL), and 6 g of creatine nitrate (CNH) for 6 days. Participants repeated the experiment with the alternate supplements after a 7-day washout. Hemodynamic responses to a postural challenge, fasting blood samples, and bench press, leg press, and cycling time ...

background: innovative bioactive films incorporated with antimicrobial agents have been recently developed for food preservation. the aim of this study was to evaluate antibacterial activity of polylactic acid (pla) films incorporated with ziziphora clinopodioides essential oil (zeo) and ethanolic propolis extract (epe) against some common food-borne pathogens. methods: the volatile chemical co...

In the present study, we investigated whether polycationic peptides affect mucin release from cultured airway goblet cells. Confluent primary hamster tracheal surface epithelial cells were metabolically radiolabeled with [3H]glucosamine for 24 h and chased for 30 min in the presence of varying concentrations of either poly-l-arginine (PLA) or poly-l-lysine (PLL) to assess the effects on [3H]muc...

OBJECTIVE Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)), a proinflammatory enzyme that predominantly circulates with low-density lipoprotein (LDL), has been shown in general populations to predict cardiovascular (CV) events. We sought to determine whether increased Lp-PLA(2) would also predict CV events in the absence of high LDL-cholesterol (LDL-C), in a population with low high-densit...

BACKGROUND Lipoprotein-associated phospholipase A2 (Lp-PLA(2)) is a novel inflammatory biomarker that is associated with increased cardiovascular disease risk independent of and additive to traditional risk factors. Lp-PLA(2) activity is correlated with the degree of inflammation in the atherosclerotic plaque. In human blood, approximately 80% of Lp-PLA(2) is associated with low-density lipopro...

UNLABELLED The purpose of this study was to determine whether exercise and/or acetaminophen (APAP) alter collagen and cross-linking in the rat gastrocnemius muscle, soleus muscle, and heart. Male Wistar rats (n = 50; 8 wk old) were divided into placebo (PLA) or APAP groups and sedentary (SED) or exercised (RUN) groups. APAP (200 mg/kg) was administered daily by oral gavage. Exercised groups ran...

An exclusive-OR transform of input variables significantly reduces the size of the PLA implementation for adder and comparator circuits. For n bit adder circuits, the size of PLA for transformed functions is O(n2). In comparison, when the complete truth-table of an adder is minimized, the PLA size will be O(2n+2). Similarly, for an n bit comparator, the size of the PLA is reduced from O(2n+1) t...

PEG–PLA hydrogels were prepared by stereocomplexation of poly(lactide) (PLA) blocks of opposite chirality. Gelation occurred upon mixing aqueous solutions of both enantiomers of PEG6500–(PLA)2, PEG12500–(PLA)2 and PEG21800–(PLA)8 block copolymers. Stereocomplexed hydrogels from PEG6500–(PLA)2 polymers were found to be stable up to ~37 8C, while those from PEG12500–(PLA)2 and PEG21800–(PLA)8 blo...

NIH3T3 cells stably expressing the rat 5-hydroxytryptamine 2A (5-HT 2A) receptor (5500 fmol/mg) were used to explore further the capacity of structurally distinct ligands to elicit differential signaling through the phospholipase C (PLC) or phospholipase A 2 (PLA 2) signal transduction pathways. Initial experiments were designed to verify that 5-HT 2A receptor-mediated PLA 2 activation in NIH3T...