نتایج جستجو برای: pivka

تعداد نتایج: 203  

2012
Toru Miyake Seiichiro Hoshino Yoichiro Yoshida Naoya Aisu Syu Tanimura Satoshi Hisano Nobuaki Kuno Tetsuro Sohda Shotaro Sakisaka Yuichi Yamashita

Ectopic hepatocellular carcinoma (HCC) is a very rare clinical entity that is defined as HCC arising from extrahepatic liver tissue. This report presents a case of ectopic multiple HCC arising in the abdominal cavity. A 42-year-old otherwise healthy male presented with liver dysfunction at a general health checkup. Both HCV antibody and hepatitis B surface antigen were negative. Laboratory exam...

2014
Hyun Jung Lee Jong Eun Yeon Sang Jun Suh Sun Jae Lee Eileen L. Yoon Keunhee Kang Yang Jae Yoo Ji Hoon Kim Yeon Seok Seo Hyung Joon Yim Kwan Soo Byun

BACKGROUND/AIMS α-Fetoprotein (AFP) is the biomarker most widely used to detect hepatocellular carcinoma (HCC), despite its suboptimal diagnostic accuracy. Glypican-3 (GPC3) and osteopontin (OPN) are secreted glycoproteins that are reportedly associated with tumorigenesis and metastasis. This study was conducted to evaluate the clinical utility of using plasma GPC3 and OPN as diagnostic biomark...

Journal: :Biochemical and biophysical research communications 2003
Tetsuya Nakatsura Yoshihiro Yoshitake Satoru Senju Mikio Monji Hiroyuki Komori Yutaka Motomura Seiji Hosaka Toru Beppu Takatoshi Ishiko Hidenobu Kamohara Hiroshi Ashihara Toyomasa Katagiri Yoichi Furukawa Shigetoshi Fujiyama Michio Ogawa Yusuke Nakamura Yasuharu Nishimura

With the global pandemic of hepatitis B and C infections, the incidence of Hepatocellular carcinoma (HCC) is rapidly increasing world wide. We identified glypican-3 (GPC3), a novel oncofetal gene over-expressed specifically in human HCC, as based on data of cDNA microarrays. As GPC3 is a GPI-anchored membrane protein and could be secreted, we attempted to detect secreted GPC3 protein in sera fr...

2015
Hideomi Yamashita Hiroshi Onishi Naoya Murakami Yasuo Matsumoto Yukinori Matsuo Takuma Nomiya Keiichi Nakagawa

Stereotactic body radiotherapy (SBRT) is a relatively new treatment for liver tumor. Outcomes of SBRT for liver tumors unsuitable for ablation or surgical resection were evaluated. A total of 79 patients treated with SBRT for primary hepatocellular carcinoma (HCC) between 2004 and 2012 in six Japanese institutions were studied retrospectively. Patients treated with SBRT preceded by trans-arteri...

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