Recurrent labial herpes simplex is a pathology of viral origin that is frequently observed in children. The signs and symptoms are uncomfortable and, in many cases, the efficacy of treatment is unproven. However, several studies have demonstrated good results from the use of low-level laser therapy (LLLT), primarily due to acceleration of the healing process and pain relief, which make it a pro...

Prostate cancer is one of the most prevalent tumors. The switch of androgen signal dependence makes therapy more complex. Although reports on introduction of a single suicide gene exist, double suicide gene therapy has not been reported yet. In the current study, two suicide genes were constructed in the pIRES plasmid driven by PSMA promoter. 5-FC and GCV combination in vitro led to a higher gr...

M. O. Soares, A. F. Vinha, S. V. P. Barreira, F. Coutinho, S. Aires-Gonçalves, M.B.P.P. Oliveira, P. C. Pires and A. Castro IPSN-CESPU/ Instituto Politécnico de Saúde do Norte, R. José António Vidal, 81, 4760-409 Vila Nova de Famalicão, Portugal. FCS/UFP/Faculdade Ciências da Saúde, Universidade Fernando Pessoa, R. Carlos da Maia, 296, 4200-150 Porto, Portugal. REQUIMTE/Dep. de Ciências Química...

In this paper, we propose a new scheme for anisotropic motion by mean curvature in R. The scheme consists of a phase-field approximation of the motion, where the nonlinear diffusive terms in the corresponding anisotropic Allen-Cahn equation are linearized in the Fourier space. In real space, this corresponds to the convolution with a specific kernel of the form Kφ,t(x) = F−1 [ e−4π 2tφo(ξ) ] (x...

Em meados do século XVIII, a expansão dos luso-brasileiros afetou os povos Jê que viviam nos sertões de Goiás e Piauí. Para tentar conter as incursões guerreiras indígenas, Coroa portuguesa contratou Antônio Pires Campos Gomes Leite visando prática guerras, assim como seus pactos criação aldeamentos partir da iniciativa particular, ou seja, sertanistas. Dessa forma, indícios das fontes literatu...