The effect of transfection of NIH 3T3 cells by the human ras (c-Ha-ras-1) oncogene on uptake, interconversion, and excretion of polyamines was studied. Uptake and interconversion of spermidine were higher in the ras-transfected cells. Acetylpolyamines were excreted into the medium by the ras-transfected cells, whereas they were retained by NIH 3T3 cells. In addition to acetylpolyamines, some un...

The creep compliance and relaxation functions used in characterizing the mechanical response of linear viscoelastic solids are traditionally found by conducting two separate experiments. Alternatively, one of the functions may be determined from a single experiment while the other is obtained through interconversion. All direct interconversion methods, however, require the solution of an ill-po...

In a complete simply connected Riemannian manifold X of pinched negative curvature, we give a sharp criterion for a subset C to be the ǫ-neighbourhood of some convex subset of X, in terms of the extrinsic curvatures of the boundary of C. 1

Resolving the origin of intratumor heterogeneity has proven to be one of the central challenges in cancer research during recent years. Two theoretical models explaining the emergence of intratumor heterogeneity have come to dominate cancer biology literature: the clonal evolution model and the hierarchical/cancer stem cell model. Recently, a plastic model that combines elements of both the clo...

Self-assembly of macromolecules with ligands is an intricate dynamic process that depends on a wide variety of parameters and forms the basis of many essential biological processes. We elucidate the underlying energetic processes of self-assembly in a model system consisting of amphiphilic core-shell polymers interacting with paramagnetic, amphiphilic ligand molecules from temperature-dependent...

In this paper, we investigate relation between weak subdifferential and augmented normal cone. We define augmented normal cone via weak subdifferential and vice versa. The necessary conditions for the global maximum are also stated. We produce preliminary properties of augmented normal cones and discuss them via the distance function. Then we obtain the augmented normal cone for the indicator f...

We prove the central limit theorem of random variables induced by distances to Brownian paths and Green functions on universal cover Riemannian manifolds finite volume with pinched negative curvature. further provide some ergodic properties motions an application dynamics geodesic flows in

‎The aim of this paper is to establish the equivalence between the concepts‎ ‎of an $S$-metric space and a cone $S$-metric space using some topological‎ ‎approaches‎. ‎We introduce a new notion of a $TVS$-cone $S$-metric space using‎ ‎some facts about topological vector spaces‎. ‎We see that the known results on‎ ‎cone $S$-metric spaces (or $N$-cone metric spaces) can be directly obtained‎ from...

Our theorems are on ordered cone metric spaces which are not necessarily normal. In the end, we describe the application of the main results in the integral equation.Although Du in [W‎. ‎S‎. ‎Du‎, ‎A note on cone metric fixed point theory and its equivalence‎, ‎Nonlinear Analysis‎, ‎72(2010) 2259-2261.]‎, ‎showed that the fixed point results in the setting of cone...